Delta Neutrophil Index as a New Early Mortality Predictor after Liver Transplantation
Abstract
1. Introduction
2. Materials and Methods
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Abbreviations
References
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30 Days Mortality (−) | 30 Days Mortality (+) | p-Value | ||||
---|---|---|---|---|---|---|
Age | 54.1 ± 8.4 | 17~72 | 51.0 ± 9.6 | 33~64 | 0.239 | |
Sex | Male | 289 | 76.05% | 8 | 61.5% | 0.8 |
Female | 91 | 23.95% | 5 | 38.5% | ||
MELD | 13.5 ± 7.5 | 5~42 | 20.7 ± 11.1 | 9~43 | 0.002 | |
OP time | 11.8 ± 2.1 | 7.2~23 | 13.1 ± 3.0 | 8~19.3 | 0.05 | |
Transfusion | 5.83 ± 9.16 | 0~97 | 29.4 ± 25.3 | 2~72 | <0.0001 | |
ICU duration | 4.58 ± 2.73 | 0~24 | 8.33 ± 4.5 | 1~16 | <0.0001 | |
Renal replacement | Yes | 2 | 0.6% | 1 | 8.3% | 0.001 |
No | 378 | 99.4% | 12 | 91.8% | ||
Pre OP CRP | 11.1 ± 22.7 | 0~216 | 21.14 ± 21.6 | 0.8~55.4 | 0.19 | |
Pre OP DNI | 1.0 ± 2.51 | 0~36.9 | 2.1 ± 2.3 | 0~7.4 | 0.18 | |
POD 7 CRP | 18.3 ± 28.3 | 0.95~168.8 | 41.6 ± 57.2 | 1.6~181.7 | 0.024 | |
POD 7 DNI | 2.1 ± 2.6 | 0~32.4 | 3.9 ± 2.9 | 0~8.2 | 0.021 | |
POD 14 CRP | 15.5 ± 22.7 | 0~130.5 | 88.9 ± 80.2 | 7.5~212 | <0.0001 | |
POD 14 DNI | 1.1 ± 1.5 | 0~12.5 | 8.2 ± 13.7 | 0.5~47.3 | <0.0001 |
DNI ≥ 2.05 on POD 14 | DNI < 2.05 on POD 14 | p-Value | ||||
---|---|---|---|---|---|---|
Age | 53.3 ± 9.5 | 17~71 | 54.2 ± 8.1 | 17~72 | 0.42 | |
Sex | Male | 44 | 60.2% | 253 | 79.5% | <0.0001 |
Female | 29 | 39.8% | 65 | 20.5% | ||
MELD | 16.4 ± 9.1 | 6~43 | 13.1 ± 7.2 | 5~42 | 0.001 | |
OP time | 12.4 ± 2.0 | 9~19.3 | 11.7 ± 2.2 | 7.2~23 | 0.017 | |
Transfusion | 10.7 ± 14.4 | 0~72 | 5.5 ± 9.2 | 0~97 | <0.0001 | |
ICU duration | 5.9 ± 3.4 | 2~17 | 4.4 ± 2.6 | 0~24 | <0.0001 | |
Renal replacement | Yes | 2 | 2.7% | 1 | 0.3% | 0.033 |
No | 71 | 37.3% | 317 | 99.7% | ||
Pre OP CRP | 12.3 ± 20.9 | 0.2~142.6 | 11.2 ± 23.2 | 0.2~216.2 | 0.74 | |
POD 7 CRP | 30.7 ± 43.2 | 2.4~181.7 | 16.3 ± 25.2 | 0.95~168.8 | 0.006 | |
POD 14 CRP | 34.6 ± 45.7 | 0.7~212.03 | 13.3 ± 21.3 | 0.4~130.45 | <0.0001 | |
30 days mortality | 9/73 | 12.3% | 2/318 | 0.6% | 0.008 |
Variable | Univariate | Multivariate | |
---|---|---|---|
p-Value | p-Value | OR (95% CI) | |
Age | 0.83 | ||
Sex | 0.95 | ||
Transfusion | 0.99 | ||
CRRT history | 0.48 | ||
MELD | 0.26 | 0.064 | 1.06 (0.99~1.15) |
OP time | 0.36 | ||
DNI ≥ 2.05 on POD 14 | 0.99 | 0.001 | 31.55 (3.83~260.3) |
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Lee, J.; Son, S.; Kim, H.; Ju, M. Delta Neutrophil Index as a New Early Mortality Predictor after Liver Transplantation. J. Clin. Med. 2023, 12, 2501. https://doi.org/10.3390/jcm12072501
Lee J, Son S, Kim H, Ju M. Delta Neutrophil Index as a New Early Mortality Predictor after Liver Transplantation. Journal of Clinical Medicine. 2023; 12(7):2501. https://doi.org/10.3390/jcm12072501
Chicago/Turabian StyleLee, Jeongjun, Sunyoung Son, Heeyoung Kim, and Manki Ju. 2023. "Delta Neutrophil Index as a New Early Mortality Predictor after Liver Transplantation" Journal of Clinical Medicine 12, no. 7: 2501. https://doi.org/10.3390/jcm12072501
APA StyleLee, J., Son, S., Kim, H., & Ju, M. (2023). Delta Neutrophil Index as a New Early Mortality Predictor after Liver Transplantation. Journal of Clinical Medicine, 12(7), 2501. https://doi.org/10.3390/jcm12072501