Short- and Long-Term Outcomes in Elderly Patients Following Hand-Assisted Laparoscopic Surgery for Colorectal Liver Metastasis
Abstract
:1. Introduction
2. Materials and Methods
2.1. Surgical Technique
2.2. Statistical Analysis
3. Results
Comparison between Patients in G1 and G2
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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ALL (n = 145) | Young (<75) (n = 117) | Old (≥75) (n = 28) | p Value | |
---|---|---|---|---|
Age (years) median | 67 (59:73) | 64 (57:70) | 80 (77:83) | 0.000 |
Gender | 0.43 | |||
Male | 89 (61%) | 70 (60%) | 19 (68%) | |
Female | 56 (39%) | 47 (40%) | 9 (32%) | |
Primary tumor location | 0.05 | |||
Right colon | 40 (28%) | 27 (23%) | 13 (47%) | |
Left colon | 65 (45%) | 54 (46%) | 11 (39%) | |
Rectum | 35 (24%) | 31 (27%) | 4 (14%) | |
Missing | 5 (3%) | 5(4%) | ||
Stage at colon diagnosis | 0.47 | |||
II | 39 (27%) | 29 (25%) | 10 (36%) | |
III | 31 (21%) | 25 (21%) | 6 (21%) | |
IV | 75 (52%) | 63 (54%) | 12 (43%) | |
Liver tumor | ||||
size of largest metastases (mm) median | 20(13:35) | 20(13:35) | 32(19:52) | 0.001 |
Number of Metastases | 0.032 | |||
1 | 77 (53%) | 56 (47%) | 21 (75%) | |
2 | 27(19%) | 24 (21%) | 3 (11%) | |
>3 | 41(28%) | 37 (32%) | 4 (14%) | |
Number, median | 1(1:3) | 2(1:3) | 1(1:2) | 0.019 |
Fong Clinical Risk Score | 0.144 | |||
Low | 100 (71%) | 77 (68%) | 23 (82%) | |
High | 41 (29%) | 36 (32%) | 5 (18%) | |
Missing | 4 | 4 | ||
Neoadjuvant therapy | 101 (70%) | 86 (74%) | 15 (53%) | 0.039 |
ALL (n = 145) | Young (<75) (n = 117) | Old (≥75) (n = 28) | p Value | |
---|---|---|---|---|
Type of liver resection | 0.003 | |||
RT lobectomy | 6 (4%) | 4 (3%) | 2 (7%) | |
LT Lobectomy | 5 (3%) | 1 (1%) | 4 (14%) | |
LLT | 22 (16%) | 17 (15%) | 5 (18%) | |
Anterior segments (non-Anatomical) | 58 (40%) | 46 (39%) | 12 (43%) | |
Posterior Segments (non-Anatomical) | 54 (37%) | 49 (42%) | 5 (18%) | |
Conversion | 8 (6%) | 5 (4%) | 3 (11%) | 0.09 |
Operative Time (min) median | 172 (125:233) | 178 (125:240) | 168 (147:235) | 0.86 |
Blood Transfusion | 34 (23%) | 26 (22%) | 8 (29%) | 0.47 |
Complications | 32(23%) | 22 (19%) | 10 (36%) | 0.06 |
Hospital stay (days) median | 6 (5:7) | 5 (4:7) | 7 (5:10) | 0.22 |
surgical margins R0 | 132 (91%) | 106 (91%) | 26 (93%) | 0.78 |
Adjuvant Chemotherapy | 102 (70%) | 79 (67%) | 23 (82%) | 0.14 |
ALL (n = 145) | Young (<75) (n = 117) | Old (≥75) (n = 28) | p Value | |
---|---|---|---|---|
Median follow-up (months) | 40 (23:56) | 41 (19:92) | 0.32 | |
Overall survival | ||||
Median (months) | 59 (48:69) | 71 (58:83) | 45 (31:58) | 0.12 |
12 (months) | 94% | 95% | 96% | |
24 (months) | 85% | 86% | 80% | |
36 (months) | 73% | 73% | 67% | |
60 (months) | 47% | 52% | 30% |
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Mahamid, A.; Abu-Zaydeh, O.; Mattar, S.; Kazlow, E.; Froylich, D.; Sawaied, M.; Goldberg, N.; Berger, Y.; Sadot, E.; Haddad, R. Short- and Long-Term Outcomes in Elderly Patients Following Hand-Assisted Laparoscopic Surgery for Colorectal Liver Metastasis. J. Clin. Med. 2023, 12, 4785. https://doi.org/10.3390/jcm12144785
Mahamid A, Abu-Zaydeh O, Mattar S, Kazlow E, Froylich D, Sawaied M, Goldberg N, Berger Y, Sadot E, Haddad R. Short- and Long-Term Outcomes in Elderly Patients Following Hand-Assisted Laparoscopic Surgery for Colorectal Liver Metastasis. Journal of Clinical Medicine. 2023; 12(14):4785. https://doi.org/10.3390/jcm12144785
Chicago/Turabian StyleMahamid, Ahmad, Omar Abu-Zaydeh, Samar Mattar, Esther Kazlow, Dvir Froylich, Muneer Sawaied, Natalia Goldberg, Yael Berger, Eran Sadot, and Riad Haddad. 2023. "Short- and Long-Term Outcomes in Elderly Patients Following Hand-Assisted Laparoscopic Surgery for Colorectal Liver Metastasis" Journal of Clinical Medicine 12, no. 14: 4785. https://doi.org/10.3390/jcm12144785