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Article

The Gender Impact Assessment among Healthcare Workers in the SARS-CoV-2 Vaccination—An Analysis of Serological Response and Side Effects

1
IRCCS San Raffaele Hospital, 20132 Milan, Italy
2
University of Parma, 43121 Parma, Italy
3
IRCCS Galeazzi Orthopaedic Institute, 20161 Milan, Italy
4
Vita-Salute San Raffaele University, 20132 Milan, Italy
*
Author to whom correspondence should be addressed.
Academic Editor: S. Louise Cosby
Vaccines 2021, 9(5), 522; https://doi.org/10.3390/vaccines9050522
Received: 17 April 2021 / Revised: 13 May 2021 / Accepted: 15 May 2021 / Published: 18 May 2021
Healthcare professionals are considered to be at high risk of exposure and spread of SARS-CoV-2, and have therefore been considered a priority group in COVID-19 vaccination campaign strategies. However, it must be assumed that the immune response is influenced by numerous factors, including sex and gender. The analysis of these factors is an impact element for stratifying the population and targeting the vaccination strategy. Therefore, a large cohort of healthcare workers participating in the Italian vaccination campaign against SARS-CoV-2 has been studied to establish the impact of sex and gender on vaccination coverage using the Gender Impact Assessment approach. This study shows a significant difference in the antibody titers among different age and sex groups, with a clear decreasing trend in antibody titers in the older age groups. Overall, the serological values were significantly higher in females; the reported side effects are more frequent in females than in males. Therefore, disaggregated data point out how the evaluation of gender factors could be essential in COVID-19 vaccination strategies. On this biomedical and social basis, suggestions are provided to improve the SARS-CoV-2 vaccination campaign in healthcare professionals. Still, they could be adapted to other categories and contexts. View Full-Text
Keywords: COVID-19; side effects; vaccination coverage; gender impact assessment COVID-19; side effects; vaccination coverage; gender impact assessment
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MDPI and ACS Style

Di Resta, C.; Ferrari, D.; Viganò, M.; Moro, M.; Sabetta, E.; Minerva, M.; Ambrosio, A.; Locatelli, M.; Tomaiuolo, R. The Gender Impact Assessment among Healthcare Workers in the SARS-CoV-2 Vaccination—An Analysis of Serological Response and Side Effects. Vaccines 2021, 9, 522. https://doi.org/10.3390/vaccines9050522

AMA Style

Di Resta C, Ferrari D, Viganò M, Moro M, Sabetta E, Minerva M, Ambrosio A, Locatelli M, Tomaiuolo R. The Gender Impact Assessment among Healthcare Workers in the SARS-CoV-2 Vaccination—An Analysis of Serological Response and Side Effects. Vaccines. 2021; 9(5):522. https://doi.org/10.3390/vaccines9050522

Chicago/Turabian Style

Di Resta, Chiara, Davide Ferrari, Marco Viganò, Matteo Moro, Eleonora Sabetta, Massimo Minerva, Alberto Ambrosio, Massimo Locatelli, and Rossella Tomaiuolo. 2021. "The Gender Impact Assessment among Healthcare Workers in the SARS-CoV-2 Vaccination—An Analysis of Serological Response and Side Effects" Vaccines 9, no. 5: 522. https://doi.org/10.3390/vaccines9050522

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