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Motivating Seasonal Influenza Vaccination and Cross-Promoting COVID-19 Vaccination: An Audience Segmentation Study among University Students

COVID-19 Vaccination Acceptance in China after It Becomes Available: A Cross-Sectional Study

by 1,2, 2, 2, 2, 3, 4, 1,4,* and 1,4,*
HEOA Group, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China
Sichuan Health Development Research Center, Chengdu 610041, China
West China Hospital, Sichuan University, Chengdu 610041, China
Institute for Healthy Cities and West China Research Center for Rural Health Development, Sichuan University, Chengdu 610041, China
Authors to whom correspondence should be addressed.
Academic Editor: Siddappa N. Byrareddy
Vaccines 2021, 9(12), 1398;
Received: 24 October 2021 / Revised: 16 November 2021 / Accepted: 22 November 2021 / Published: 25 November 2021
The outbreak of coronavirus disease 2019 (COVID-19) has led to numerous tragic deaths all over the world. Great efforts have been made by worldwide nations for COVID-19 targeted vaccine development since the disease outbreak. In January 2021, the Chinese government started to provide free vaccination among nationwide communities, which was optional for citizens. As no evidence has been provided so far regarding COVID-19 vaccination acceptance since the initiation of nationwide vaccination, this study aims to investigate COVID-19 vaccination acceptance among Chinese citizens as well as its associated factors as an attempt to bridge such gap embedded in the current literature. An anonymous cross-sectional study was conducted online in March and April 2021 among adults, with the survey questionnaire designed based on the framework of the health belief model (HBM). Information on socio-demographics, risk perception, past pandemic-related experience, awareness of vaccination as well as acceptance of COVID-19 vaccination were collected. Chi-squared test and multi-level regression were performed to distinguish the acceptance between different groups as well as to identify the significant predictors. A total of 3940 participants completed the survey, with 90.6% of the participants reporting strong willingness to get vaccinated. A list of factors were found to be significantly associated with individuals’ acceptance of vaccination, including the region of residence, ethnicity, annual income, whether or not they had experienced a major pandemic event in the past, risk perception of the COVID-19 as well as the awareness of receiving vaccination. Safety concerns about the vaccine (27.7%), concerns about receiving vaccination immediately after newly developed vaccines were released into the market (22.4%) as well as concerns about the potential side effects induced by vaccination (22.1%) were identified as the primary reasons of residents’ resistance against vaccination. Overall, residents demonstrated strong willingness to receive vaccination against COVID-19 in China. However, the improvement of vaccination-related knowledge among Chinese residents should be highlighted as a critical strategy to facilitate the penetration of nationwide vaccination in order to ultimately achieve the establishment of herd immunity in China. View Full-Text
Keywords: COVID-19; vaccine acceptance; SARS-CoV-2; China; health belief model COVID-19; vaccine acceptance; SARS-CoV-2; China; health belief model
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MDPI and ACS Style

Zhou, Q.; Tian, T.; Ni, J.; Zhao, X.; Li, H.; Yang, Y.; Zhang, Y.; Pan, J. COVID-19 Vaccination Acceptance in China after It Becomes Available: A Cross-Sectional Study. Vaccines 2021, 9, 1398.

AMA Style

Zhou Q, Tian T, Ni J, Zhao X, Li H, Yang Y, Zhang Y, Pan J. COVID-19 Vaccination Acceptance in China after It Becomes Available: A Cross-Sectional Study. Vaccines. 2021; 9(12):1398.

Chicago/Turabian Style

Zhou, Qian, Tian Tian, Jie Ni, Xiaoheng Zhao, Hong Li, Yili Yang, Yumeng Zhang, and Jay Pan. 2021. "COVID-19 Vaccination Acceptance in China after It Becomes Available: A Cross-Sectional Study" Vaccines 9, no. 12: 1398.

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