Omics and Bioinformatics Approaches to Identify Novel Antigens for Vaccine Investigation and Development
1
iBB—Institute for Bioengineering and Biosciences, and Bioengineering Department, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisbon, Portugal
2
Department of Biochemistry and Molecular Biology, University of Córdoba, Campus de Excelencia Internacional CeiA3, 14071 Córdoba, Spain
*
Author to whom correspondence should be addressed.
Vaccines 2020, 8(4), 653; https://doi.org/10.3390/vaccines8040653
Received: 23 October 2020 / Accepted: 2 November 2020 / Published: 3 November 2020
(This article belongs to the Special Issue Omics and Bioinformatics Approaches to Identify Novel Antigens for Vaccine Investigation and Development)
Despite the outstanding technological advances achieved in the last few decades, infectious diseases remain a major societal challenge. From the variolation carried out in ancient China during the 15th century to the more advanced RNA and DNA vaccines presently available, vaccines have been proven as highly effective therapeutic tools to combat various infectious diseases. Vaccine research and development is now empowered with recent advances in Omics sciences and the developments of powerful bioinformatics tools. This Special Issue has gathered a total of nine original papers, including seven research papers and two reviews, illustrating the use of Omics data and bioinformatics in the research, design and development of vaccines against pathogens and cancer. The integration of knowledge from Omics and Bioinformatics will certainly boost vaccine research and development, leading to novel therapeutic tools against new and old pathogens and cancer in the near future.
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Keywords:
omics; genomics; proteomics; antigen identification; bioinformatics tools; subunit vaccine; high-throughput techniques
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
MDPI and ACS Style
Leitão, J.H.; Rodríguez-Ortega, M.J. Omics and Bioinformatics Approaches to Identify Novel Antigens for Vaccine Investigation and Development. Vaccines 2020, 8, 653. https://doi.org/10.3390/vaccines8040653
AMA Style
Leitão JH, Rodríguez-Ortega MJ. Omics and Bioinformatics Approaches to Identify Novel Antigens for Vaccine Investigation and Development. Vaccines. 2020; 8(4):653. https://doi.org/10.3390/vaccines8040653
Chicago/Turabian StyleLeitão, Jorge H.; Rodríguez-Ortega, Manuel J. 2020. "Omics and Bioinformatics Approaches to Identify Novel Antigens for Vaccine Investigation and Development" Vaccines 8, no. 4: 653. https://doi.org/10.3390/vaccines8040653
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