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Open AccessArticle

Cross-Sectional Study on the Sero- and Viral Dynamics of Porcine Circovirus Type 2 in the Field

by Chao-Nan Lin 1,2,*, Ni-Jyun Ke 1 and Ming-Tang Chiou 1,2,*
1
Animal Disease Diagnostic Center, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung 91201, Taiwan
2
Department of Veterinary Medicine, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung 91201, Taiwan
*
Authors to whom correspondence should be addressed.
Vaccines 2020, 8(2), 339; https://doi.org/10.3390/vaccines8020339
Received: 15 May 2020 / Revised: 24 June 2020 / Accepted: 24 June 2020 / Published: 26 June 2020
(This article belongs to the Section Veterinary Vaccines)
Porcine circovirus-associated diseases (PCVADs) cause considerable economic losses in industrial pork production in the field. To minimize the economic losses due to PCVAD, porcine circovirus type 2 (PCV2) vaccines have been developed, and there is widespread vaccination worldwide today. However, limited information is available concerning the current status of PCV2 infection in the field on the Asian continent. The present study aimed to assess sero- and viral dynamics of PCV2 from 12 PCV2-contaminated pig herds with vaccination against PCV2 in Southern and Central Taiwan. In particular, the level of PCV2 load during the window period for seroconversion using real-time polymerase chain reaction and a commercial enzyme-linked immunosorbent assay (ELISA) kit. Our results revealed that pig herds showed slight or no seroconversion after three to four weeks post-PCV2 immunization. The presence of PCV2 was observed during the window period for seroconversion in all herds. In conclusion, natural exposure of PCV2 occurs in the growing to fattening period, and viremia can last until slaughter. Additionally, our findings indicate that using ELISA showed the level of antibodies and aided in the understanding and surveillance of the current PCV2 status in the field. View Full-Text
Keywords: porcine circovirus type 2; porcine circovirus-associated diseases; ELISA; real-time PCR porcine circovirus type 2; porcine circovirus-associated diseases; ELISA; real-time PCR
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MDPI and ACS Style

Lin, C.-N.; Ke, N.-J.; Chiou, M.-T. Cross-Sectional Study on the Sero- and Viral Dynamics of Porcine Circovirus Type 2 in the Field. Vaccines 2020, 8, 339.

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