Next Article in Journal
Identification of Naturally Processed Epitope Region Using Artificial APC Expressing a Single HLA Class I Allotype and mRNA of HCMV pp65 Antigen Fragments
Next Article in Special Issue
Serious Underlying Medical Conditions and COVID-19 Vaccine Hesitancy: A Large Cross-Sectional Analysis from Australia
Previous Article in Journal
Chimeric Virus-like Particle-Based COVID-19 Vaccine Confers Strong Protection against SARS-CoV-2 Viremia in K18-hACE2 Mice
Previous Article in Special Issue
COVID-19 Vaccine Hesitancy among Behavioral Risk Takers
 
 
Article

Missed Opportunities for Vaccination and Associated Factors among Children Attending Primary Health Care Facilities in Cape Town, South Africa: A Pre-Intervention Multilevel Analysis

1
Division of Epidemiology and Biostatistics, School of Public Health and Family Medicine, University of Cape Town, Cape Town 7925, South Africa
2
Cochrane South Africa, South African Medical Research Council, Cape Town 7501, South Africa
3
Division of Epidemiology and Biostatistics, Department of Global Health, Stellenbosch University, Cape Town 7505, South Africa
4
HIV and Other Infectious Diseases Research Unit, South African Medical Research Council, Cape Town 7501, South Africa
5
Western Cape Provincial Department of Health, Cape Town 8000, South Africa
6
Division of Health Systems and Public Health, Department of Global Health, Stellenbosch University, Cape Town 7505, South Africa
*
Author to whom correspondence should be addressed.
Academic Editor: Giuseppe La Torre
Vaccines 2022, 10(5), 785; https://doi.org/10.3390/vaccines10050785
Received: 28 March 2022 / Revised: 4 May 2022 / Accepted: 12 May 2022 / Published: 16 May 2022
Despite the substantial efforts at ensuring universal access to routine immunisation services among children in South Africa, major gaps in immunisation coverage remain. This study assessed the magnitude of missed opportunities for vaccination (MOV) and associated factors among children aged 0–23 months attending primary health care (PHC) facilities in Cape Town. We used multilevel binomial logistic regression models to explore individual and contextual factors associated with MOV, with children aged 0–23 months at Level 1, nested within PHC facilities (Level 2). A total of 674 children and their caregivers were enrolled. MOV prevalence was 14.1%, ranging from 9.1% to 18.9% across sub-districts. Dose-specific MOV prevalence was highest for the second dose of measles vaccine (9.5%) and lowest for the first dose of rotavirus vaccine (0.6%). The likelihood of a child experiencing MOV was significantly associated with caregivers’ low level of education (Odds ratio (OR) = 3.53, 95% credible interval (CrI): 1.13–11.03), recent receipt of immunisation messages (OR = 0.46, 95%CrI: 0.25–0.87), shared immunisation decision making by both parents (OR = 0.21, 95%CrI: 0.07–0.62) and health facility staff number (OR = 0.18, 95%CrI: 0.06–0.61). The burden of MOV among children in Cape Town is influenced by individual and contextual factors, which provide important opportunities for quality improvement and broader strategies to improve routine immunisation service delivery. View Full-Text
Keywords: missed opportunities for vaccination; vaccination; immunisation; children; primary health care; quality improvement; South Africa missed opportunities for vaccination; vaccination; immunisation; children; primary health care; quality improvement; South Africa
Show Figures

Figure 1

MDPI and ACS Style

Nnaji, C.A.; Wiysonge, C.S.; Adamu, A.A.; Lesosky, M.; Mahomed, H.; Ndwandwe, D. Missed Opportunities for Vaccination and Associated Factors among Children Attending Primary Health Care Facilities in Cape Town, South Africa: A Pre-Intervention Multilevel Analysis. Vaccines 2022, 10, 785. https://doi.org/10.3390/vaccines10050785

AMA Style

Nnaji CA, Wiysonge CS, Adamu AA, Lesosky M, Mahomed H, Ndwandwe D. Missed Opportunities for Vaccination and Associated Factors among Children Attending Primary Health Care Facilities in Cape Town, South Africa: A Pre-Intervention Multilevel Analysis. Vaccines. 2022; 10(5):785. https://doi.org/10.3390/vaccines10050785

Chicago/Turabian Style

Nnaji, Chukwudi A., Charles S. Wiysonge, Abdu A. Adamu, Maia Lesosky, Hassan Mahomed, and Duduzile Ndwandwe. 2022. "Missed Opportunities for Vaccination and Associated Factors among Children Attending Primary Health Care Facilities in Cape Town, South Africa: A Pre-Intervention Multilevel Analysis" Vaccines 10, no. 5: 785. https://doi.org/10.3390/vaccines10050785

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop