Next Article in Journal
Neuroinflammation in Post-Traumatic Epilepsy: Pathophysiology and Tractable Therapeutic Targets
Previous Article in Journal
Left-Hemispheric Asymmetry for Object-Based Attention: an ERP Study
Open AccessPerspective

Intracerebral Hemorrhage: Blood Components and Neurotoxicity

Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta University, 1120 15th Street, Augusta, GA 30912, USA
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Brain Sci. 2019, 9(11), 316;
Received: 26 September 2019 / Revised: 30 October 2019 / Accepted: 7 November 2019 / Published: 9 November 2019
Intracerebral hemorrhage (ICH) is a subtype of stroke which is associated with the highest mortality and morbidity rates of all strokes. Although it is a major public health problem, there is no effective treatment for ICH. As a consequence of ICH, various blood components accumulate in the brain parenchyma and are responsible for much of the secondary brain damage and ICH-induced neurological deficits. Therefore, the strategies that could attenuate the blood component-induced neurotoxicity and improve hematoma resolution are highly needed. The present article provides an overview of blood-induced brain injury after ICH and emphasizes the need to conduct further studies elucidating the mechanisms of hematoma resolution after ICH. View Full-Text
Keywords: ICH; hemin; thrombin; hemoglobin; iron ICH; hemin; thrombin; hemoglobin; iron
Show Figures

Figure 1

MDPI and ACS Style

Madangarli, N.; Bonsack, F.; Dasari, R.; Sukumari–Ramesh, S. Intracerebral Hemorrhage: Blood Components and Neurotoxicity. Brain Sci. 2019, 9, 316.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Back to TopTop