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Enhancement of High-Intensity Focused Ultrasound Heating by Short-Pulse Generated Cavitation

1
Department of Communications Engineering, Graduate School of Engineering, Tohoku University, Sendai 980-8579, Japan
2
Department of Biomedical Engineering, Graduate School of Biomedical Engineering, Tohoku University, Sendai 980-8579, Japan
*
Author to whom correspondence should be addressed.
Academic Editor: Kohji Masuda
Appl. Sci. 2017, 7(3), 288; https://doi.org/10.3390/app7030288
Received: 28 October 2016 / Revised: 22 February 2017 / Accepted: 3 March 2017 / Published: 16 March 2017
(This article belongs to the Special Issue Biomedical Ultrasound)
A target tissue can be thermally coagulated in high-intensity focused ultrasound (HIFU) treatment noninvasively. HIFU thermal treatments have been clinically applied to various solid tumors. One of the problems in HIFU treatments is a long treatment time. Acoustically driven microbubbles can accelerate the ultrasonic heating, resulting in the significant reduction of the treatment time. In this paper, a method named “trigger HIFU exposure” which employs cavitation microbubbles is introduced and its results are reviewed. A trigger HIFU sequence consists of high-intensity short pulses followed by moderate-intensity long bursts. Cavitation bubbles induced in a multiple focal regions by rapidly scanning the focus of high-intensity pulses enhanced the temperature increase significantly and produced a large coagulation region with high efficiency. View Full-Text
Keywords: HIFU; focused ultrasound; cavitation; microbubble; ultrasound imaging HIFU; focused ultrasound; cavitation; microbubble; ultrasound imaging
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MDPI and ACS Style

Yoshizawa, S.; Takagi, R.; Umemura, S.-i. Enhancement of High-Intensity Focused Ultrasound Heating by Short-Pulse Generated Cavitation. Appl. Sci. 2017, 7, 288. https://doi.org/10.3390/app7030288

AMA Style

Yoshizawa S, Takagi R, Umemura S-i. Enhancement of High-Intensity Focused Ultrasound Heating by Short-Pulse Generated Cavitation. Applied Sciences. 2017; 7(3):288. https://doi.org/10.3390/app7030288

Chicago/Turabian Style

Yoshizawa, Shin, Ryo Takagi, and Shin-ichiro Umemura. 2017. "Enhancement of High-Intensity Focused Ultrasound Heating by Short-Pulse Generated Cavitation" Applied Sciences 7, no. 3: 288. https://doi.org/10.3390/app7030288

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