Evaluation of the Possible Ameliorative Effects of Anemarrhena asphodeloides Extract on Liver Cirrhosis by Combining Biochemical Analysis and Electrical Tissue Conductivity
Abstract
:1. Introduction
2. Materials and Methods
2.1. Preparation of Anemarrhena asphodeloides Extract
2.2. Animal Preparation
2.3. Histology and Immunohistochemisty
2.4. Serum Biochemistry
2.5. Western Blotting
2.6. Statistical Analysis
2.7. Electrical Conductivity Measurements
3. Results
3.1. Body Weight Measurement and Serum Biochemical Assay
3.2. Histological Analysis
3.3. Effects on α-SMA and COX-2 Expression
3.4. Improving Effects of AAE by Western Blot Analysis
3.5. Improving Effects of AAE by Electrical Conductivity Imaging
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Parameters | Normal | DMN Only | DMN + AAE | DMN + Lac |
---|---|---|---|---|
AST (IU/L) | 77.3 ± 12.1 * | 205.7 ± 25.4 | 103.5 ± 21.2 | 119.3 ± 17.9 |
ALT (IU/L) | 32.5 ± 4.9 | 74.7 ± 4.6 | 53.3 ± 5.3 | 51.8 ± 3.8 |
Albumin (g/dL) | 3.9 ± 0.2 | 2.9 ± 0.4 | 3.8 ± 0.3 | 3.7 ± 0.1 |
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Kim, Y.; Kim, J.W.; Choi, B.K.; Katoch, N.; Yoon, E.J.; Kim, J.S.; Hur, Y.H.; Song, S.G.; Kim, H.J. Evaluation of the Possible Ameliorative Effects of Anemarrhena asphodeloides Extract on Liver Cirrhosis by Combining Biochemical Analysis and Electrical Tissue Conductivity. Appl. Sci. 2023, 13, 7950. https://doi.org/10.3390/app13137950
Kim Y, Kim JW, Choi BK, Katoch N, Yoon EJ, Kim JS, Hur YH, Song SG, Kim HJ. Evaluation of the Possible Ameliorative Effects of Anemarrhena asphodeloides Extract on Liver Cirrhosis by Combining Biochemical Analysis and Electrical Tissue Conductivity. Applied Sciences. 2023; 13(13):7950. https://doi.org/10.3390/app13137950
Chicago/Turabian StyleKim, Youngsung, Jin Woong Kim, Bup Kyung Choi, Nitish Katoch, Eun Ju Yoon, Jong Seon Kim, Young Hoe Hur, Sang Gook Song, and Hyung Joong Kim. 2023. "Evaluation of the Possible Ameliorative Effects of Anemarrhena asphodeloides Extract on Liver Cirrhosis by Combining Biochemical Analysis and Electrical Tissue Conductivity" Applied Sciences 13, no. 13: 7950. https://doi.org/10.3390/app13137950