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Open AccessReview
Disease Prediction in Cattle: A Mixed-Methods Review of Predictive Modeling Studies
by
Lilli Heinen
Lilli Heinen 1,
Robert L. Larson
Robert L. Larson 2
and
Brad J. White
Brad J. White 2,*
1
Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66502, USA
2
Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66502, USA
*
Author to whom correspondence should be addressed.
Animals 2025, 15(17), 2481; https://doi.org/10.3390/ani15172481 (registering DOI)
Submission received: 19 July 2025
/
Revised: 19 August 2025
/
Accepted: 21 August 2025
/
Published: 23 August 2025
Simple Summary
Predictive models use historical data to make future predictions. These tools have become more common in the cattle industry in recent years. Their applications are broad but they are especially useful in the prediction of disease. This review explores published studies that use predictive models to predict health outcomes in cattle. Various data types and health outcomes were investigated to characterize predictive model accuracy. Models performed with low and high accuracies depending on outcome, algorithm, and data types. Several challenges were highlighted including data quality and access and rare disease outcomes. This review shows the importance of using more than one performance metric, using easy-to-collect and informative data, and demonstrates that future work should focus on improving how models handle rare outcomes.
Abstract
Predictive models use historical data to predict a future event and can be applied to a wide variety of tasks. A broader evaluation of the cattle literature is required to better understand predictive model performance across various health challenges and to understand data types utilized to train models. This narrative review aims to describe predictive model performance in greater detail across various disease outcomes, input data types, and algorithms with a specific focus on accuracy, sensitivity, specificity, and positive and negative predictive values. A secondary goal is to address important areas for consideration for future work in the beef cattle sector. In total, 19 articles were included. Broad categories of disease were covered, including respiratory disease, bovine tuberculosis, and others. Various input data types were reported, including demographic data, images, and laboratory test results, among others. Several algorithms were utilized, including neural networks, linear models, and others. Accuracy, sensitivity, and specificity values ranged widely across disease outcome and algorithm categories. Negative predictive values were greater than positive predictive values for most disease outcomes. This review highlights the importance of utilizing several performance metrics and concludes that future work should address prevalence of outcomes and class-imbalanced data.
Share and Cite
MDPI and ACS Style
Heinen, L.; Larson, R.L.; White, B.J.
Disease Prediction in Cattle: A Mixed-Methods Review of Predictive Modeling Studies. Animals 2025, 15, 2481.
https://doi.org/10.3390/ani15172481
AMA Style
Heinen L, Larson RL, White BJ.
Disease Prediction in Cattle: A Mixed-Methods Review of Predictive Modeling Studies. Animals. 2025; 15(17):2481.
https://doi.org/10.3390/ani15172481
Chicago/Turabian Style
Heinen, Lilli, Robert L. Larson, and Brad J. White.
2025. "Disease Prediction in Cattle: A Mixed-Methods Review of Predictive Modeling Studies" Animals 15, no. 17: 2481.
https://doi.org/10.3390/ani15172481
APA Style
Heinen, L., Larson, R. L., & White, B. J.
(2025). Disease Prediction in Cattle: A Mixed-Methods Review of Predictive Modeling Studies. Animals, 15(17), 2481.
https://doi.org/10.3390/ani15172481
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