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Article

A Pectin-Rich, Baobab Fruit Pulp Powder Exerts Prebiotic Potential on the Human Gut Microbiome In Vitro

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Döhler GmbH, 64295 Darmstadt, Germany
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Cryptobiotix SA, 9052 Ghent, Belgium
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ProDigest BV, 9052 Ghent, Belgium
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Center of Microbial Ecology and Technology (CMET), Ghent University, 9000 Ghent, Belgium
*
Author to whom correspondence should be addressed.
Academic Editor: Garry X. Shen
Microorganisms 2021, 9(9), 1981; https://doi.org/10.3390/microorganisms9091981
Received: 29 July 2021 / Revised: 4 September 2021 / Accepted: 10 September 2021 / Published: 17 September 2021
(This article belongs to the Special Issue Nutritional Regulation on Gut Microbiota)
Increasing insight into the impact of the gut microbiota on human health has sustained the development of novel prebiotic ingredients. This exploratory study evaluated the prebiotic potential of baobab fruit pulp powder, which consists of pectic polysaccharides with unique composition as compared to other dietary sources, given that it is rich in low methoxylated homogalacturonan (HG). After applying dialysis procedures to remove simple sugars from the product (simulating their absorption along the upper gastrointestinal tract), 48 h fecal batch incubations were performed. Baobab fruit pulp powder boosted colonic acidification across three simulated human adult donors due to the significant stimulation of health-related metabolites acetate (+18.4 mM at 48 h), propionate (+5.5 mM at 48 h), and to a lesser extent butyrate (0.9 mM at 48 h). Further, there was a trend of increased lactate levels (+2.7 mM at 6h) and reduced branched chain fatty acid (bCFA) levels (−0.4 mM at 48 h). While Bacteroidetes levels increased for all donors, donor-dependent increases in Bifidobacteria, Lactobacilli, and Firmicutes were observed, stressing the potential interindividual differences in microbial composition modulation upon Baobab fruit pulp powder treatment. Overall, Baobab fruit pulp powder fermentation displayed features of selective utilization by host microorganisms and, thus, has promising prebiotic potential (also in comparison with the ‘gold standard’ prebiotic inulin). Further research will be required to better characterize this prebiotic potential, accounting for the interindividual differences, while aiming to unravel the potential resulting health benefits. View Full-Text
Keywords: baobab fruit pulp powder; prebiotic; pectin; interindividual variation; in vitro; gut microbiota; dialysis baobab fruit pulp powder; prebiotic; pectin; interindividual variation; in vitro; gut microbiota; dialysis
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MDPI and ACS Style

Foltz, M.; Zahradnik, A.C.; Van den Abbeele, P.; Ghyselinck, J.; Marzorati, M. A Pectin-Rich, Baobab Fruit Pulp Powder Exerts Prebiotic Potential on the Human Gut Microbiome In Vitro. Microorganisms 2021, 9, 1981. https://doi.org/10.3390/microorganisms9091981

AMA Style

Foltz M, Zahradnik AC, Van den Abbeele P, Ghyselinck J, Marzorati M. A Pectin-Rich, Baobab Fruit Pulp Powder Exerts Prebiotic Potential on the Human Gut Microbiome In Vitro. Microorganisms. 2021; 9(9):1981. https://doi.org/10.3390/microorganisms9091981

Chicago/Turabian Style

Foltz, Martin, Alicia C. Zahradnik, Pieter Van den Abbeele, Jonas Ghyselinck, and Massimo Marzorati. 2021. "A Pectin-Rich, Baobab Fruit Pulp Powder Exerts Prebiotic Potential on the Human Gut Microbiome In Vitro" Microorganisms 9, no. 9: 1981. https://doi.org/10.3390/microorganisms9091981

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