Microbial Biofilms and Chronic Wounds
Abstract
:1. Introduction—Microbial Biofilms
2. Biofilm Formation
3. Quorum Sensing
4. Biofilm Resistance
5. Biofilm Structure and Morphology
6. Biofilms in Chronic Wounds
7. Identification of Drug Resistance/Tolerance, Susceptibility, and Treatments
8. Research on New Treatment Strategies
- Signals and cues:
- AIP-1 (Gram-positive bacteria)—controls the agr system based on quorum sensing such that disassembly of the biofilm is coupled to increased density or decreased nutrient availability, causing release of proteases and pore-forming toxins, and increased expression of virulence factors [100,104,105,106]
- Cell envelope-modifying molecules:
9. Summary
Acknowledgments
Conflicts of Interest
References
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Omar, A.; Wright, J.B.; Schultz, G.; Burrell, R.; Nadworny, P. Microbial Biofilms and Chronic Wounds. Microorganisms 2017, 5, 9. https://doi.org/10.3390/microorganisms5010009
Omar A, Wright JB, Schultz G, Burrell R, Nadworny P. Microbial Biofilms and Chronic Wounds. Microorganisms. 2017; 5(1):9. https://doi.org/10.3390/microorganisms5010009
Chicago/Turabian StyleOmar, Amin, J. Barry Wright, Gregory Schultz, Robert Burrell, and Patricia Nadworny. 2017. "Microbial Biofilms and Chronic Wounds" Microorganisms 5, no. 1: 9. https://doi.org/10.3390/microorganisms5010009