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Pathogens 2013, 2(1), 1-12;

Human Bocavirus: Lessons Learned to Date

Kliniken der Stadt Köln gGmbH, Krankenhaus Merheim, Klinikum der Privaten Universität Witten/Herdecke, Institut für Pathologie, Ostmerheimer Str. 200, D-51109 Köln (Cologne), Germany
Received: 10 December 2012 / Revised: 8 January 2013 / Accepted: 8 January 2013 / Published: 11 January 2013
(This article belongs to the Special Issue Pathogen Infection Models)
Full-Text   |   PDF [183 KB, uploaded 11 January 2013]


Human bocavirus (HBoV) was identified as the second human parvovirus with pathogenic potential in 2005 in respiratory samples from children suffering from viral respiratory infections of unknown etiology. Since its first description, a large number of clinical studies have been performed that address the clinical significance of HBoV detection and the molecular biology of the virus. This review summarizes the most important steps taken in HBoV research to date and addresses open questions that need to be answered in the future to provide a better understanding of the role of a virus that is difficult to grow in cell culture and is suspected to be a pathogen, although it has not yet fulfilled Koch’s postulates. View Full-Text
Keywords: human bocavirus; HBoV; respiratory virus; gastrointestinal virus human bocavirus; HBoV; respiratory virus; gastrointestinal virus
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Schildgen, O. Human Bocavirus: Lessons Learned to Date. Pathogens 2013, 2, 1-12.

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