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J. Pers. Med. 2017, 7(3), 7; https://doi.org/10.3390/jpm7030007

Empowering Mayo Clinic Individualized Medicine with Genomic Data Warehousing

Mayo Clinic, Rochester, MN, 55905, USA
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Author to whom correspondence should be addressed.
Academic Editor: Stephen B. Liggett
Received: 13 June 2017 / Revised: 28 July 2017 / Accepted: 2 August 2017 / Published: 22 August 2017
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Abstract

Individualized medicine enables better diagnoses and treatment decisions for patients and promotes research in understanding the molecular underpinnings of disease. Linking individual patient’s genomic and molecular information with their clinical phenotypes is crucial to these efforts. To address this need, the Center for Individualized Medicine at Mayo Clinic has implemented a genomic data warehouse and a workflow management system to bring data from institutional electronic health records and genomic sequencing data from both clinical and research bioinformatics sources into the warehouse. The system is the foundation for Mayo Clinic to build a suite of tools and interfaces to support various clinical and research use cases. The genomic data warehouse is positioned to play a key role in enhancing the research capabilities and advancing individualized patient care at Mayo Clinic. View Full-Text
Keywords: personalized medicine; precision medicine; next-generation sequencing; NGS; genomic variant call format; gVCF; pharmacogenomics; translational research personalized medicine; precision medicine; next-generation sequencing; NGS; genomic variant call format; gVCF; pharmacogenomics; translational research
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Horton, I.; Lin, Y.; Reed, G.; Wiepert, M.; Hart, S. Empowering Mayo Clinic Individualized Medicine with Genomic Data Warehousing. J. Pers. Med. 2017, 7, 7.

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