Primary Mucinous Cystadenocarcinoma of the Breast Intermixed with Pleomorphic Invasive Lobular Carcinoma: The First Report of This Rare Association
Abstract
:1. Introduction
2. Case Report
3. Discussion
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Conflicts of Interest
References
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Case | Age (Years) | Size (cm) | DCIS | ER/PR/HER2 | CK7/CK20 | Nodal Metastasis | Treatment | Follow-Up |
---|---|---|---|---|---|---|---|---|
1 [1] | 79 | 6 | + | NA | NA/NA | - | Mastectomy | DOD, 24 months |
2 [2] | 54 | 19 | - | -/-/NA | +/- | + | Mastectomy, Lymph node dissection | ANED, 24 months |
3 [2] | 67 | 2.3 | + | -/-/NA | +/- | - | Mastectomy, Lymph node dissection | ANED, 22 months |
4 [2] | 49 | 8.5 | + | -/-/NA | +/- | - | Mastectomy, Lymph node dissection, Chemotherapy, Radiotherapy | ANED, 11 months |
5 [2] | 61 | 0.8 | - | -/-/NA | +/- | - | Lumpectomy, Lymph node dissection | NA |
6 [3] | 74 | 10 | + | -/NA/NA | +/- | - | Mastectomy, Lymph node dissection | ANED, 24 months |
7 [4] | 96 | 2 | - | -/-/- | NA/NA | + | Lumpectomy, Lymph node dissection | ANED, 46 months |
8 [5] | 65 | 3 | + | -/-/- | +/+ (focal) | - | Mastectomy, Lymph node dissection, Chemotherapy | ANED, 8 months |
9 [6] | 51 | 4 | - | -/-/NA | +/- | - | Lumpectomy | NA |
10 [7] | 55 | 2.5 | + | -/-/-/ | +/- | - | Lumpectomy | ANED, 6 months |
11 [8] | 52 | 10 | - | +/-/- | -/- | - | Mastectomy, Lymph node dissection | ANED, 24 months |
12 [9] | 61 | 3 | - | -/-/- | NA/- | - | Mastectomy, Lymph node dissection | ANED, 6 months |
13 [10] | 73 | 4.5 | + | -/-/2+ | +/- | - | Mastectomy, Lymph node dissection | NA |
14 [11] | 65 | 3 | + | -/-/NA | +/- | + | Partial mastectomy, Lymph node dissection | ANED, 6 months |
15 [12] | 52 | 6.5 | - | -/-/- | +/- | - | NA | NA |
16 [13] | 41 | 7 | + | -/-/- | +/- | - | Mastectomy, Lymph node dissection | ANED, 24 months |
17 [14] | 59 | 0.9 | + | -/-/2+ | +/- | - | Partial mastectomy, lymph node dissection, Chemotherapy | ANED, 3 months |
18 [15] | 62 | 5.6 | - | -/-/- | +/- | - | Mastectomy, Lymph node dissection | ANED, 15 months |
19 [16] | 55 | 2 | + | -/-/2+ | +/- | - | Mastectomy, Lymph node dissection, Chemotherapy, Radiotherapy | ANED, 10 months |
20 [17] | 91 | 7.5 | + | -/-/- | +/- | - | Mastectomy, Radiotherapy | DOD, 14 months |
21 [18] | 59 | 2 | - | -/-/3+ | NA/NA | - | Partial mastectomy | NA |
22 [18] | 50 | 2.2 | - | -/-/- | NA/NA | - | Partial mastectomy | NA |
23 [19] | 63 | 1.6 | - | -/-/- | +/- | + | Lumpectomy, Lymph node dissection, Chemotherapy, Radiotherapy | ANED, 48 months |
24 [20] | 58 | 4.5 | + | -/-/- | +/- | - | Mastectomy, Lymph node dissection | ANED, 6 months |
25 [21] | 68 | 6.2 | + | -/-/- | +/- | - | Lumpectomy, Sentinel lymph node dissection | ANED, 3 months |
26 [21] | 59 | 2 | + | -/-/- | +/- | - | Lumpectomy, lymph node dissection | Alive with local recurrence after 96 months |
27 [22] | 56 | 2 | - | +/+/- | -/- | - | Mastectomy, Lymph node dissection | ANED, 3 months |
28 [23] | 68 | 4 | NA | -/-/- | +/- | - | Mastectomy, Lymph node dissection | ANED, 21 months |
29 [24] | 45 | 4.3 | + | -/-/- | +/- | - | Lumpectomy, Mastectomy, Lymph node dissection, Chemotherapy, Radiotherapy | ANED, 6 months |
30 [25] | 69 | 2 | + | +/+/- | NA | - | NA | NA |
31 [26] | 66 | 2.5 | + | -/-/- | +/- | - | Mastectomy, Lymph node dissection | ANED, 13 months |
32 [27] | 65 | 18 | - | -/-/3+ | +/focal + | NA | Mastectomy | ANED, 6 months |
33 [28] | 72 | 0.9 | - | -/-/- | +/- | - | Mastectomy, Lymph node dissection | ANED, 16 moths |
34 [29] | 61 | 3.5 | + | +/+/- | +/- | + | Mastectomy, Lymph node dissection | ANED, 8 months |
35 [30] | 61 | 2.5 | + | -/-/- | +/- | - | Mastectomy, Lymph node dissection | ANED, 10 months |
36 [31] | 59 | 3 | - | -/-/- | +/- | - | Lumpectomy, Lymph node dissection | ANED, 108 months |
Present Case | 41 | 1.5 | - | +/-/- | +/NA | Isolated Tumor Cells | Partial mastectomy, sentinel lymph node dissection | ANED, 11 months |
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Vegni, F.; D’Alessandris, N.; Santoro, A.; Angelico, G.; Scaglione, G.; Carlino, A.; Arciuolo, D.; Valente, M.; Sfregola, S.; Natale, M.; et al. Primary Mucinous Cystadenocarcinoma of the Breast Intermixed with Pleomorphic Invasive Lobular Carcinoma: The First Report of This Rare Association. J. Pers. Med. 2023, 13, 948. https://doi.org/10.3390/jpm13060948
Vegni F, D’Alessandris N, Santoro A, Angelico G, Scaglione G, Carlino A, Arciuolo D, Valente M, Sfregola S, Natale M, et al. Primary Mucinous Cystadenocarcinoma of the Breast Intermixed with Pleomorphic Invasive Lobular Carcinoma: The First Report of This Rare Association. Journal of Personalized Medicine. 2023; 13(6):948. https://doi.org/10.3390/jpm13060948
Chicago/Turabian StyleVegni, Federica, Nicoletta D’Alessandris, Angela Santoro, Giuseppe Angelico, Giulia Scaglione, Angela Carlino, Damiano Arciuolo, Michele Valente, Stefania Sfregola, Maria Natale, and et al. 2023. "Primary Mucinous Cystadenocarcinoma of the Breast Intermixed with Pleomorphic Invasive Lobular Carcinoma: The First Report of This Rare Association" Journal of Personalized Medicine 13, no. 6: 948. https://doi.org/10.3390/jpm13060948