Next Article in Journal
Clinical and Laboratory Associations with Methotrexate Metabolism Gene Polymorphisms in Rheumatoid Arthritis
Next Article in Special Issue
Definition of Personalized Medicine and Targeted Therapies: Does Medical Familiarity Matter?
Previous Article in Journal
Characterisation of MRI Indeterminate Breast Lesions Using Dedicated Breast PET and Prone FDG PET-CT in Patients with Breast Cancer—A Proof-of-Concept Study
Previous Article in Special Issue
Comprehensive Custom NGS Panel Validation for the Improvement of the Stratification of B-Acute Lymphoblastic Leukemia Patients
Review

Personalized Medicine for Antibiotics: The Role of Nanobiosensors in Therapeutic Drug Monitoring

1
PhD Biosciences Program, Universidad de La Sabana, Chía 140013, Colombia
2
Therapeutical Evidence Group, Clinical Pharmacology, Universidad de La Sabana, Chía 140013, Colombia
*
Author to whom correspondence should be addressed.
J. Pers. Med. 2020, 10(4), 147; https://doi.org/10.3390/jpm10040147
Received: 21 August 2020 / Revised: 5 September 2020 / Accepted: 7 September 2020 / Published: 25 September 2020
(This article belongs to the Special Issue Personalized Medicine in Clinical Practice)
Due to the high bacterial resistance to antibiotics (AB), it has become necessary to adjust the dose aimed at personalized medicine by means of therapeutic drug monitoring (TDM). TDM is a fundamental tool for measuring the concentration of drugs that have a limited or highly toxic dose in different body fluids, such as blood, plasma, serum, and urine, among others. Using different techniques that allow for the pharmacokinetic (PK) and pharmacodynamic (PD) analysis of the drug, TDM can reduce the risks inherent in treatment. Among these techniques, nanotechnology focused on biosensors, which are relevant due to their versatility, sensitivity, specificity, and low cost. They provide results in real time, using an element for biological recognition coupled to a signal transducer. This review describes recent advances in the quantification of AB using biosensors with a focus on TDM as a fundamental aspect of personalized medicine. View Full-Text
Keywords: biosensors; therapeutic drug monitoring (TDM), antibiotic; personalized medicine biosensors; therapeutic drug monitoring (TDM), antibiotic; personalized medicine
Show Figures

Graphical abstract

MDPI and ACS Style

Garzón, V.; Bustos, R.-H.; G. Pinacho, D. Personalized Medicine for Antibiotics: The Role of Nanobiosensors in Therapeutic Drug Monitoring. J. Pers. Med. 2020, 10, 147. https://doi.org/10.3390/jpm10040147

AMA Style

Garzón V, Bustos R-H, G. Pinacho D. Personalized Medicine for Antibiotics: The Role of Nanobiosensors in Therapeutic Drug Monitoring. Journal of Personalized Medicine. 2020; 10(4):147. https://doi.org/10.3390/jpm10040147

Chicago/Turabian Style

Garzón, Vivian, Rosa-Helena Bustos, and Daniel G. Pinacho. 2020. "Personalized Medicine for Antibiotics: The Role of Nanobiosensors in Therapeutic Drug Monitoring" Journal of Personalized Medicine 10, no. 4: 147. https://doi.org/10.3390/jpm10040147

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop