Next Article in Journal
An Assessment of Early Response to Targeted Therapy via Molecular Imaging: A Pilot Study of 3′-deoxy-3′[(18)F]-Fluorothymidine Positron Emission Tomography 18F-FLT PET/CT in Prostate Adenocarcinoma
Next Article in Special Issue
Ten Important Considerations for Ovarian Cancer Screening
Previous Article in Journal / Special Issue
Symptoms Relevant to Surveillance for Ovarian Cancer
Article Menu
Issue 2 (June) cover image

Export Article

Open AccessArticle

Ovarian Cancer Incidence Corrected for Oophorectomy

The Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, The University of Kentucky College of Medicine, 800 Rose Street, 330 Whitney-Hendrickson Building, Lexington, KY 40536, USA
Division of Cancer Biostatistics, College of Public Health & Biostatistics Shared Resource Facility, Markey Cancer Center, University of Kentucky, Lexington, KY 40506, USA
Department of Epidemiology, College of Public Health & Kentucky Cancer Registry, Markey Cancer Center, University of Kentucky, Lexington, KY 40506, USA
Kentucky Department for Public Health, Frankfort, KY 40601, USA
Author to whom correspondence should be addressed.
Academic Editor: Tanya W. Moseley
Diagnostics 2017, 7(2), 19;
Received: 30 December 2016 / Revised: 1 March 2017 / Accepted: 18 March 2017 / Published: 1 April 2017
(This article belongs to the Special Issue Ovarian Cancer Screening)
PDF [379 KB, uploaded 1 April 2017]


Current reported incidence rates for ovarian cancer may significantly underestimate the true rate because of the inclusion of women in the calculations who are not at risk for ovarian cancer due to prior benign salpingo-oophorectomy (SO). We have considered prior SO to more realistically estimate risk for ovarian cancer. Kentucky Health Claims Data, International Classification of Disease 9 (ICD-9) codes, Current Procedure Terminology (CPT) codes, and Kentucky Behavioral Risk Factor Surveillance System (BRFSS) Data were used to identify women who have undergone SO in Kentucky, and these women were removed from the at-risk pool in order to re-assess incidence rates to more accurately represent ovarian cancer risk. The protective effect of SO on the population was determined on an annual basis for ages 5–80+ using data from the years 2009–2013. The corrected age-adjusted rates of ovarian cancer that considered SO ranged from 33% to 67% higher than age-adjusted rates from the standard population. Correction of incidence rates for ovarian cancer by accounting for women with prior SO gives a better understanding of risk for this disease faced by women. The rates of ovarian cancer were substantially higher when SO was taken into consideration than estimates from the standard population. View Full-Text
Keywords: ovarian cancer; prevalence; incidence; oophorectomy; screening ovarian cancer; prevalence; incidence; oophorectomy; screening

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Supplementary material

Printed Edition Available!
A printed edition of this Special Issue is available here.

Share & Cite This Article

MDPI and ACS Style

Baldwin, L.A.; Chen, Q.; Tucker, T.C.; White, C.G.; Ore, R.N.; Huang, B. Ovarian Cancer Incidence Corrected for Oophorectomy. Diagnostics 2017, 7, 19.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Diagnostics EISSN 2075-4418 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top