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18F-FDG PET/CT Findings in Acute Epstein-Barr Virus Infection Mimicking Malignant Lymphoma

1
Department of Infectious Diseases, Copenhagen University Hospital Hvidovre, Kettegaards Allé 30, DK-2650 Hvidovre, Denmark
2
Department of Clinical Physiology & Nuclear Medicine, Copenhagen University Hospital, DK-2650 Hvidovre, Denmark
3
Department of Radiology, Copenhagen University Hospital Hvidovre, DK-2650 Hvidovre, Denmark
*
Author to whom correspondence should be addressed.
Academic Editor: Markus Schwaiger
Diagnostics 2016, 6(2), 18; https://doi.org/10.3390/diagnostics6020018
Received: 28 February 2016 / Revised: 18 April 2016 / Accepted: 10 May 2016 / Published: 12 May 2016
(This article belongs to the Special Issue Positron Emission Tomography (PET) in Cardiology and Oncology)
We present a case demonstrating the diagnostic work-up and follow-up of a patient with acute Epstein-Barr virus (EBV) infection in which the clinical picture and imaging on 18F-FDG PET/CT mimicked malignant lymphoma. Follow-up 18F-FDG PET/CT scan in the patient performed 7 weeks after the abnormal scan revealed complete resolution of the metabolically active disease in the neck, axillas, lung hili, and spleen. This case highlights inflammation as one of the most well established false positives when interpreting 18F-FDG PET/CT scans. View Full-Text
Keywords: Epstein-Barr virus; 18F-FDG PET/CT; lymphadenopathy; infectious mononucleosis; malignant lymphoma Epstein-Barr virus; 18F-FDG PET/CT; lymphadenopathy; infectious mononucleosis; malignant lymphoma
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Ørbæk, M.; Graff, J.; Markova, E.; Kronborg, G.; Lebech, A.-M. 18F-FDG PET/CT Findings in Acute Epstein-Barr Virus Infection Mimicking Malignant Lymphoma. Diagnostics 2016, 6, 18.

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