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Article
Peer-Review Record

Visual Assessment and Longitudinal Strain During Dobutamine Stress Echocardiography

Diagnostics 2025, 15(12), 1473; https://doi.org/10.3390/diagnostics15121473
by Dijana Trninić 1,2,*, Jelena Jovanic 1,2, Aleksandar Lazarevic 1,2, Miron Marjanovic 1, Sinisa Kovacevic 1, Neno Dobrijevic 1 and Snjezana Pejicic Popovic 1,2
Reviewer 1:
Reviewer 2: Anonymous
Diagnostics 2025, 15(12), 1473; https://doi.org/10.3390/diagnostics15121473
Submission received: 28 April 2025 / Revised: 19 May 2025 / Accepted: 28 May 2025 / Published: 10 June 2025
(This article belongs to the Special Issue Advances in the Diagnosis and Management of Cardiovascular Diseases)

Round 1

Reviewer 1 Report

Comments and Suggestions for Authors

An interesting study showing the correlation between visual assessment of contractility and strain measurements. I have 3 main questions: 1. Were patients rejected from the study if accurate strain measurements could not be obtained? Surely not all patients was strain able to be analyzed at rest and peak? 2. Was the visual analysis of wall motion performed independently of strain analysis - ie blinded? 3. Why do they conclude that "The application of longitudinal strain during dobutamine stress echocardiography increases the accuracy of these diagnostic method"?

Author Response

Dear Reviewer, please check our reply in the attachment.

Author Response File: Author Response.pdf

Reviewer 2 Report

Comments and Suggestions for Authors
  1. Although the study results are good, strain echo is not a practical application.

  2. I wonder that did you  do interobserver (kappa statistics ?) and intra-observer (correlation coeeficent?) reliability test?

  3. How were the anlaysis done ? on-record or off-record?

  4. Is there statistical evidence of a good correlation between LS and DSE?

  5. How much can it change our daily practice?

  6. Both introduction and discussion in main text is too long. 

  7. The English should be improved.
Comments on the Quality of English Language
  1. Although the study results are good, strain echo is not a practical application.

  2. I wonder that did you  do interobserver (kappa statistics ?) and intra-observer (correlation coeeficent?) reliability test?

  3. How were the anlaysis done ? on-record or off-record?

  4. Is there statistical evidence of a good correlation between LS and DSE?

  5. How much can it change our daily practice?

  6. Both introduction and discussion in main text is too long. 

  7. The English should be improved.

Author Response

Dear Reviewer 2, please check our reply in the attachment

Author Response File: Author Response.pdf

Round 2

Reviewer 2 Report

Comments and Suggestions for Authors

Thank you for this revision 

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