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Diagnostics
  • Article
  • Open Access

15 March 2024

DengueFog: A Fog Computing-Enabled Weighted Random Forest-Based Smart Health Monitoring System for Automatic Dengue Prediction

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1
Chitkara University Institute of Engineering and Technology, Chitkara University, Punjab 140401, India
2
Department of Computer Science and Engineering, Jaypee University of Information Technology, Waknaghat, Solan 173234, India
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Department of Computer Science & Engineering, Chandigarh University, Gharuan, Mohali 140413, India
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School of Computer Science and Artificial Intelligence, SR University, Warangal 506371, India
This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics

Abstract

Dengue is a distinctive and fatal infectious disease that spreads through female mosquitoes called Aedes aegypti. It is a notable concern for developing countries due to its low diagnosis rate. Dengue has the most astounding mortality level as compared to other diseases due to tremendous platelet depletion. Hence, it can be categorized as a life-threatening fever as compared to the same class of fevers. Additionally, it has been shown that dengue fever shares many of the same symptoms as other flu-based fevers. On the other hand, the research community is closely monitoring the popular research fields related to IoT, fog, and cloud computing for the diagnosis and prediction of diseases. IoT, fog, and cloud-based technologies are used for constructing a number of health care systems. Accordingly, in this study, a DengueFog monitoring system was created based on fog computing for prediction and detection of dengue sickness. Additionally, the proposed DengueFog system includes a weighted random forest (WRF) classifier to monitor and predict the dengue infection. The proposed system’s efficacy was evaluated using data on dengue infection. This dataset was gathered between 2016 and 2018 from several hospitals in the Delhi-NCR region. The accuracy, F-value, recall, precision, error rate, and specificity metrics were used to assess the simulation results of the suggested monitoring system. It was demonstrated that the proposed DengueFog monitoring system with WRF outperforms the traditional classifiers.

1. Introduction

The illnesses transmitted by mosquitoes are deadly in nature and spread swiftly from infected to uninfected individuals via bacteria, viruses, and parasites [1]. The bite of a female mosquito infected with the virus is the primary cause of transmission [2]. In addition, the infected individual needs to be monitored regularly to diagnose a particular disease and to determine a suitable legal therapy [3] These lethal infections include filariasis, malaria, West Nile fever, chikungunya, Zika virus, yellow fever, and dengue fever. The speedy blowout of this pollution is an outcome of a developing transportation network, environmental and climatic change, and the inability to control mosquito reproduction [4]. The cautioning symptoms and indicators of these lethal diseases remain almost identical; hence, it is quite difficult to distinguish and classify the exact condition. Therefore, for identifying the specific condition, patients must undertake numerous medical tests [5]. Because of the growing number of infected individuals and insufficient health care resources, these tests are not administered to the majority of patients. Consequently, subsequent treatment and imprecise diagnosis contribute to a high fatality rate, thereby promoting a hike in mosquito-borne diseases [6]. Thus, it is a big problem for government health care insurance companies to identify mosquito-borne illnesses at an initial phase and prevent their rapid transmission. To treat the majority of mosquito-borne diseases, there is no specific therapy or drug [7]. Thus, an intelligent framework is required to identify and prevent the rapid spread of mosquito-borne illnesses from the outset. The patients affected by a disease transmitted by mosquitoes require regular surveillance. Patients are not always able to visit a hospital or health care facility for routine checkups. Thus, a remote health care monitoring system may be created to promote ubiquitous health care services utilizing emerging technical interventions such as Internet of Things (IoT), wearable devices, cloud computing, wireless sensors, fog computing [8,9]. These technologies can be utilized for the surveillance of key patient indicators and the provision of compassionate treatment. In modern sensing technologies, numerous wearable gadgets such as inconspicuous, smart fabrics, and printable electronic tattoos are employed [10,11,12,13]. The purpose of these gadgets is to collect individual health data in order to anticipate a healthy lifestyle [14,15]. In addition, wireless sensor mobile computing paradigms are frequently utilized in the health care arena for data collecting and processing, despite the fact that the storage capacity of mobile phones is ample for processing health-related data [16,17].
Due to centralized storage and advanced calculation facilities [18,19], cloud computing is also utilized in medical informatics. Numerous health care applications employ IoT as the vital acquisition module for creating a smart environment [20,21]. IoT is capable of managing, storing, and analyzing voluminous amounts of data. Cloud computing, on the other hand, offers resources based on the pay-per-service model. Multiple IoT-based applications make use of these services. One of them is the remote health care monitoring system [22,23,24]. Various computer tools, such as cloud computing, wireless sensors, and mobile computing, are being used to boost the quality of health care amenities [25]. The advantages of cloud computing include storage size, availability, cost-effectiveness, scalability, and accessibility. These characteristics help government agencies create remote health monitoring systems [26]. In addition, unprecedented volumes of health data are kept in the cloud-based data centers. Consequently, the price of health care amenities is drastically decreased [27]. Moreover, the framework allowed by cloud computing efficiently monitors patients affected by mosquito-borne diseases and seamlessly uses the medical records across clinics for efficient administration of health statistics [28,29]. Managing enormous amounts of data on the cloud, however, is extraordinarily difficult, and it slows the transmission across the internet, which can have dire effects such as endangering the lives of patients [30]. In addition, processing overhead, traffic across network, movement, location consciousness, and correspondence overhead may develop. In context of patients’ personal information in medical informatics [31,32,33], privacy breaches and threats are another concern. Fog computing might be seen as a solution to the aforementioned issues and limitations of cloud computing. It can function as an intermediate between the end user and the cloud server for providing health care services and resources [34].
Between centralized cloud infrastructure and the IoT is a stratum of fog computing for managing messaging overhead, latency, decision-making, resident storage, and information preprocessing problems between the end user and the cloud server [35,36,37]. Integration of IoT, fog computation, and the cloud enhances scalability and agility for controlling the mosquito-borne diseases by incorporating topographical areas and assessments based on real-world data analytics [38]. It provides enhanced support to the Nano Data Centers in terms of data storage and consumes minimum power compared to cloud computing. It is the consequence of time consumption, application type, download counts, information pre-loading, upgrades, and type of network accessed [39].
In recent years, researchers have paid a great deal of attention to eHealth care applications in an effort to attain a healthy lifestyle with confidence and excitement, as well as to improve well-being. The e-health applications must be accurate and must focus on the patient. Such applications need constant patient health statistics, yet those data are insufficient for accurately forecasting the illness status. It further needs contextual data for diagnostic extraction [40]. Therefore, contextual information, patient input, and patient profile information may be used to generate more precise patient-centric suggestions and diagnoses [41]. The projected fog-based health monitoring system has the following prime objectives:
To develop a fog and IoT- based health monitoring arrangement to allow remote diagnosis of dengue infection based on a patient’s health symptoms.
To provide immediate treatment to dengue-infected patients, monitor infected patients, and routinely issue health-specific alert messages. Continuous monitoring and timely notifications of blood pressure fluctuations should also be provided, allowing users and physicians to make health decisions.
To have an effective framework for sharing medical records in order to give preventive measures and recommendations based on the present condition of hypertension.

3. Proposed Monitoring System Based on Fog Computing

This section exemplifies the discussed DengueFog system. The main aim of DengueFog system is early prediction or identification, prevention, and monitoring of dengue infection. Figure 1 illustrates the architecture of the proposed fog-based smart health monitoring system. The DengueFog system can be utilized to predict the dengue infection as well as inform the concerned stakeholders by generating the alarm in the condition of a positive result. The DengueFog system has two spaces, namely cyberspace and the physical space. The breeding places, mosquito count, patient’s personal information, symptoms, and contact information are all captured in the physical space. In cyberspace, fog and cloud computing are combined to process the data and a powerful cyber–physical system is designed for health care application areas. Cloud servers are used to store vast amounts of data and process large amounts of data. However, an intermediary fog computing system was deployed to deliver lower latency and location consciousness. It also allows real-time applications to use emergency notification services. A smart health monitoring system consists of four layers. The layers are data collection layer (DCL), fog computing gateway layer (FCGL), cloud processing layer (CPL), and end user layer (EUL). The DCL collects the real-time information from diverse sensors, including the physiological data of users, mosquito density, geographical location, and contextual information. This information or data is represented as environment data, health data, behavioral data, location data, motion data, and private data.
Figure 1. Architecture of proposed fog computing-based monitoring system.
To evaluate and diagnose the data, the collected data are forwarded to the fog computing gateway layer. An ensemble classifier is employed in this layer to forecast dengue fever. Once dengue is anticipated, patients are notified by alert message so that preventive measures can be performed. The cloud layer’s job is to store processed data and distribute it to medical professionals, health care facilities, and patients’ families. The information is also utilized to estimate the dengue fever’s effects in a certain area. Users who will visit these locations can also receive some cautionary warnings. Figure 2 and Figure 3 illustrate the proposed DengueFog monitoring system’s flowchart. The flowchart demonstrates how each layer of the proposed monitoring system operates.
Figure 2. Operational sequence of the proposed monitoring system-based on fog computing.
Figure 3. Flowchart of cloud, fog, and IoT layer to share and sense dengue data.

3.1. Patient Information Layer

The patient information layer is in charge of gathering user information based on environmental factors and sickness symptoms. The data are categorized as behavioral, personal, activity, health data. The information is gathered using a variety of wearable gadgets and sensors positioned on the subject’s body and in their environment. Additionally, using WSN technologies, the captured data are communicated in a real-time context. The following IoT sensor types are utilized to gather the required dataset of information for dengue surveillance.
  • Health Dataset: Information about dengue disease symptoms can be found in the health dataset. Vomit, a fever, rashes, body aches, headaches, abdominal pain, chills, etc., are a few of the symptoms. These kinds of data are gathered for each person using a health sensor. These health sensors are Wearable Sensors like fitness trackers, smartwatches, or other health monitoring gadgets. These devices may continuously collect data on various health parameters, including body temperature, heart rate, and activity levels. For specific symptoms such as fever, body aches, and rashes, non-invasive sensors like infrared thermometers or cameras may be used to measure body temperature and detect skin conditions. Some symptoms, such as vomiting, abdominal pain, and headaches, may require self-reporting by individuals, where they input their symptoms into a health app or system.
  • Environmental Dataset: Information about people’s physical surroundings is included in this dataset. In case of dengue disease, the important parameter are mosquitoes, their breeding, and locations. The other factor that can be considered for dengue disease is water sources in terms of pond, well, cooler, etc., where mosquitoes can breed. Sometimes, humidity level, temperature, rainfall parameters are also taken into consideration.
  • Location Dataset: It contains the information of suspected and infected people of dengue disease. Further, the location of mosquito breeding and population is also one of the important parameters. In addition, RFID tag is used for close proximity.
  • Personal Dataset: Each person’s personal information is included in the data. This dataset’s attributes include sex, address, name, qualification, occupation, etc. Therefore, each individual’s confidential information is stored in a personal dataset. Table 2 summarizes the different datasets including possible attributes and attribute types. The procedural steps of patient information layer are summarized to Algorithm 1.
    Table 2. A summary of the information of different datasets collected in this study.
Algorithm 1: Procedural Steps of Patient Layer
Step 1:Collect the personal and behavioral data of patients.
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Generate the unique id of each patient.
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Enter the basic information of patient like age, gender, weight, qualification, etc.
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Enter the behavioral information of patients such as occupation, working, etc.
Step 2:Collect the patient physiological and health data.
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Put wearable IoT devices on student body.
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Collect the data related to temperature, BMI, BP, CH, etc., of the patient.
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Collect health-related data of the patient like vomiting, joint pain, itching, muscle pain, skin redness, feeling of nausea, tense muscle etc.
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Synchronize the structured and unstructured data of the patient.
Step 3:Collect the environmental and location data.
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Determine the environmental data such as humidity, rainfall, temperature, etc.
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Determine the location data such as breeding side count, mosquito density, mosquito breeding sites etc.
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Synchronize the heterogeneous data related to environmental and location attributes.
Step 4:Data Transmission
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Transfer the collected data to fog layer using wireless technologies.
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Security issues should be ensured during data transfer process.

3.2. Fog Computing Gateway Layer

The fog computing gateway layer lies among the cloud and the patient information layer. This layer deals with processing and analyzing real-time data obtained from various IoT devices and sensors, as well as identifying patients who may have dengue infection. An alert message will be generated and sent to the appropriate patient if the patient has dengue infection (infectious, positive, and recover). Additionally, this layer is linked to the cloud layer on which the patient data are stored. Alert generation and dengue classification are the two elements that make up this layer. The procedural steps for fog computing layer are summarized in Algorithm 2.
Algorithm 2: Steps of fog computing Layer
Step 1:Retrieve the data from repository on fog layer.
Step 2:Perform the preprocessing technique on collected data.
Step 3:Applied random forest classifier for dengue prediction (Algorithm 3).
Step 4:Adopted Gini Index based feature selection algorithm.
Step 5:Monitor the dengue affected patients and generate an alert message (Algorithm 4).
Step 6:Store the data on fog computing layer for future perspective.

3.2.1. Dengue Prediction

The data on dengue are divided into four classes by this module. According to Table 3, these categories are negative, infectious, positive, and recover. The patient information layer is in charge of gathering real-time, unprocessed health, personal, activity, behavioral, environmental, dengue, and IoT sensor data.
Table 3. Dengue class classifications and description.
At the fog computing layer, the data are analyzed using techniques like missing value imputation. The resulting dataset is used to forecast the dengue infection and is diverse in character. The heterogeneous dengue dataset is assembled using fog node and is transformed into a special format for dengue infection prediction. Weighted random forest classifier is utilized in the fog computing layer to forecast dengue infection in patients. The proposed weighted RF classifier’s operational procedures are provided in Algorithm 3.
Algorithm 3: Weighted random forest algorithm for dengue prediction
Input: Dengue Training Partition (P), Count of Trees (N), Features Subset—Random (FS)
Output: Random Forest (RF)
Tree with Dengue Prediction
For each i = 1 to N, do:
Apply bootstrap algorithm on training partition (P) such as P i = bootstrap   P .
Apply the Decision Tree (DT), DT i = Random   Decision   Tree   P ,   FS .
Build the RF as   RF = RF DT i .
End for
For each i = 1 to N, do:
Calculate the weight ( w i t ) of ith sample using Equation (1).
w i t = 1 OB j ϵ OB X pred   i , j X actual   i , j
End for
For each i = 1 to N, do:
i = f AUC w t IB i , AUC w t oB i
End for
For each i = 1 to, do:
Calculate the weight ( w i ) using Equation (3).
w i = N p i + 1 k k = 1 NT N p i + 1   k  
For each i = 1 to N, do:
Calculate the Final Prediction using Equation (4).
X _ pred i = 1 NT j = 1 NT X _ pred i , j × w j
End for
Return RF.

3.2.2. Alert Generation and Monitoring

The history and progress reports of the infected patients are periodically checked. The people who have contracted dengue are thought to be monitored at frequent intervals. In general, infectious patients are observed every three hours, and positive patients every ten. Patients recovering from dengue may take a variety of times and may vary depending on the advice of their doctor. As a result, the Probability of Dengue Index (PDI), which may be calculated using Equation (5), is used to monitor the patient.
PDI = P G H 1 H 2 H n
Equation (1) shows the probability, the current dengue class (G), and the severity of the occurrence (H1, H2…, Hn). By following the discovery of dengue infection, a message of alert is transmitted via the fog computing layer. This alert message is delivered to the end user’s registered mobile number and consists of various PDI ranges. Patients, patients’ families, hospitals, and doctors are examples of end users. A dengue negative alert message is delivered to end users if the PDI value is normal. Users receive a warning message with information on dengue infection, if the PDI number is abnormal. These warning messages can aid medical professionals in making an early diagnosis of dengue infection. The patient can then receive the appropriate care and safety measures in response to the effects of the dengue virus. Additionally, the proposed system can reassess the dengue illness and produce alert messages. The procedure for patient monitoring is summarized in Algorithm 4.
Algorithm 4: Process of patient monitoring
Step 1:If (Patient_Status == Dengue_Positive)
Step 2:An alert message is sent patient regarding the dengue and suggest the list of paneled hospitals.
Step 3:Take the appointment in the hospital and book the doctor.
Step 4:Send the message to doctor regarding the patient health status.
Step 5:Else if (Patient_Status == Infectious)
Step 6:Inform the doctor and patient regarding the dengue infection.
Step 7:An advisory is issued regarding the dengue for the patient.
Step 8:Else if (Patient_Status == Recover)
Step 9:Book the patient for dengue test.
Step 10:Check the test results, if satisfactory, give advisory for further precaution.
Step 11:Else (Patient_Status == Dengue_Negative)
Step 12:No symptoms of dengue is detected in patient
Step 13:End if
Step 14:Add the entry of patient into dengue dataset.

3.3. Cloud Layer

The processed data are stored for communication purposes in the DengueFog monitoring system using a cloud layer. Data about patients are kept on the ubiquitous cloud layer, which is accessible from anywhere at any time. The cloud database is currently not shared. It includes details about the user’s health state, personal information, social contact data, and medical history. This mode protects the privacy of the data from unauthorized access and contains highly sensitive information.
Additionally, two different sorts of authorized users can access the stored data via the cloud layer. Hospitals, doctors, or patients’ families are among these users. Affected subjects and their families can view the patient’s health report and leave comments regarding their experiences, health, and treatment. Similar patients utilize this input to guide their care in a proper and exact manner. However, in order to treat patients, hospitals and medical professionals access the patient’s data. The cloud layer’s operational procedures are displayed in Algorithm 5.
Algorithm 5: Process of the cloud layer
Step 1:If (Patient_Id == Exist) for storing the data into cloud repository
Step 2:Update the patient information and store it.
Step 3:Else
Generate the patient id.
Create a new data record in the dengue dataset.
Store the information of new patient in repository.
End if
Step 4:To access the data from cloud repository, do following
Step 5:If (User == Doctor)
-check the doctor id in database.
if (doctor_id == mapped)
Access the data on cloud layer
Else
Unauthorized user
End if
Step 6:Else if (User == Patient)
Check the patient id in database.
if (Patient_id == mapped)
Access the data on cloud layer
Else
Unauthorized user
End if
Step 7:Else
User is unauthorized, access is not granted.
End if

4. Experimental Results

The experimental findings of the suggested DengueFog system are presented in this section. The system’s effectiveness was evaluated using the real-time dengue data set. The dataset contained the data of dengue patients of year 2018–2020 from the Delhi-NCR region. According to Table 3, there are four classes. Additionally, a WRF classifier was used in the proposed system to forecast patient dengue infection. A Windows 10 computer with an Intel Core i5 (7th generation) processor, 8 GB of RAM, and an NVIDIA GEFORCE GPU and CPU operating at 2.70 GHz was used to build the classifier. The experimental setting was further separated into three phases, including Performance Measurement, Evaluation of the Evolution of Proposed System, and Evaluation of Alert Generation.

4.1. Performance Management

The various performance parameters used to assess the performance of the proposed system are accuracy, F-value, specificity, precision, sensitivity, and error rate [70,71,72,73].
  • Accuracy of a proposed system is defined as the ratio of accurately predicted samples to the total number of samples. For example, if there are 100 users in the dataset, 9 of them are suffering from dengue infection, but the system predicts zero dengue patient, the systems accuracy is 91/100 = 0.91%. The prediction’s accuracy is calculated by following equation:
    A c c u r a c y = T P + T N T P + T N + F P + F N
where, TP, FP, FN, and TN represent the True Positive, False Positive, False Negative, and True Negative, respectively.
  • Precision is determined as the percentage of accurately predicted positive sample to total number of positive samples, along with FP samples. For example, if 9 dengue patients are predicted by system out of 100, but there are only 3 genuinely infected patients, the predicted precision is 3/9 = 0.333%. The prediction’s precision is computed by following equation:
        P r e c i s i o n = T P T P + F P
  • Recall/Sensitivity is the ratio of correct positive samples to total positive samples; for example, if 7 dengue patients are correctly predicted by the system and 4 patients are mistakenly predicted, but in reality, there are 8 patients, the recall is 7/8 = 87.5%.
    R e c a l l = T P T P + F N
  • F-Value is defined as harmonic mean of recall and precision. It is measured as follows:
F-Value = 2 x r e c a l l p r e c i s i o n r e c a l l + p r e c i s i o n
  • Specificity is the probability of a positive samples, how many patients who do not have the dengue infection and obtained negative results? It is defined using equation.
      S p e c i f i c i t y = T N T N + F P
  • Error Rate is the percentage of instances a decision model has categorized a sample incorrectly.

4.2. Evaluation of Proposed Monitoring System Based on Fog Computing

The experimental outcome of the suggested system with WRF is compared with the existing models: Decision Tree (DT), Naive Bayes (NB), Boosting, Random Forest (RF), Artificial Neural Network (ANN), and Support Vector Machine (SVM) [49,74,75,76,77]. The proposed approach and the aforementioned classifiers’ performance comparison are shown in Table 4. As can be seen, the proposed approach outperforms the traditional classifiers. Additionally, it has been shown that WRF-based health monitoring systems achieve higher precision, specificity, recall, sensitivity, accuracy, F-value rate, and lower error rates. Additionally, the DT classifier is the worst performing model. The F-value, recall, precision, accuracy, and specificity of proposed system are increased, respectively, by 35.49 %, 33.84%, 37.06%, 14.47, 12.25% from NB classifier, 39.38%, 38.85%, 40.06%, 19.64%, 13.74% from SVM classifier, 44.93%, 46.16%, 44.06%, 19.81%, 12.44% from DT classifier, 10.38%, 11.04%,10.06%, 5.34%, 4.24% from ANN classifier, 35.65%, 31.18%, 39.18%, 13.55%, 5.79% from Boosting classifier, and 10.3%, 8.46%, 12.17%, 5.37%, 1.35% from RF classifier. The error rate is decreased by 17.47%, 21.64%, 24.51%, 7.14%, 16.55% and 8.37% from NB, SVM, ANN, Boosting, and RF classifier.
Table 4. Performance comparison of proposed DengueFog system with WRF classifier and traditional models.
A graphic representation of the specificity, F-value, error rate, accuracy, precision, and sensitivity rate to show efficiency of the models is shown in Figure 4. It is concluded that the proposed WRF classifier achieved a higher specificity, F-value, accuracy, precision, and sensitivity rate, and lower error rate for the dengue dataset, while the DT classifier offered the worst performance. Based on the experimental study, the following points are highlighted demonstrated in Figure 4:
Figure 4. Performance comparison of proposed DengueFog system with WRF classifier and traditional classifiers.
  • WRF classifier is used in the proposed system to forecast dengue illness, and it performs with a higher accuracy than RF. Because the effectiveness of RF classifiers relies on the quantity of the decision trees produced, RF cannot retain generality on small size hardware. In this work, the weighted technique is combined with the RF technique to solve the drawbacks of RF. The purpose of this amalgamation is to retain the generalization of RF even with fewer decision trees by leveraging the fact that sequential training creates complementary DT for training samples.
  • It has been shown that NB and Boosting classifiers perform somewhat differently overall, particularly for the F-value and accuracy metrics. This is because both classifiers utilize distinct objective functions to predict dengue illness. Further, the Boosting classifier increases the time, complexity, and computation.
  • The performance of the RF classifier is observed to be superior to that of the NB, Boosting, SVM, ANN, and DT classifiers. This is due to RF’s ability to be parallelized, to handle unbalanced data, its excellent high-dimensionality performance, quick prediction or fast training speed, resistance to non-linear data, moderate variance, and low bias.
  • ANN depicts the complicated relationship between output and input. Therefore, it performed better than NB, Boosting, SVM, and DT classifiers.
  • The DT classifier performs low compared to the other classifiers, because data are not separated linearly and they ignore some important variables in the training data.
The result of proposed system with the 10- fold cross validation technique is also presented in Table 5. Furthermore, Table 6 presents the evaluation results of the proposed system with detailed dengue class-wise performance analysis of the proposed system. The outcomes illustrate that the proposed system has a higher accuracy rate when it comes to predicting infected and recover people. The average accuracy of the proposed system with RFB is 93.64%. The RFB has an average recall of 88.31%. The higher precision rate, i.e., 84.62%, is generated by these higher accuracy and recall values, allowing the proposed system to minimize the error rate. Furthermore, the RFB generates less prediction errors due to its overall better specificity value of 95.29%. Similarly, higher F-value (86.27) and accuracy (93.64) values show that the RFB-based prediction is more accurate. Hence, it is concluded that the performance level fetched from the aforesaid parameters explains the use of RFB in the suggested system for fog-based health monitoring system.
Table 5. 10-Fold classification results of proposed system.
Table 6. Detailed dengue class-wise performance of WRFB.

4.3. Evaluation of Alert Generation

The suggested fog-based alert module offers timely information to the doctor, patient, patient’s family, and hospital about the dengue infection diagnosis. The reliability of response time and generated warnings were deemed the essential characteristics for determining the alert generation module efficiency. The proposed alert generation module was thoroughly investigated to determine its efficacy in delivering accurate and timely alerts to the doctor, patient, patient’s family, and hospital. The proposed fog-based alert module was tested on a snapdragon 636 1.8 Ghz with Octa-core processor and smartphone with 4 GB of memory and compared with EC2-based cloud instance alert generation system with no fog computing provision but with the same WRF prediction technique. Both systems were tested on the same dataset. The response time for both systems was measured from the time an event occurs to the time the warning about the event is generated and provided to the stakeholders. The alerts’ accuracy was determined in terms of the infection diagnosis procedure’s capacity to determine the genuine alarms. Table 7 compares the performance of the proposed fog-based and existing cloud-based alert generation module using various parameters such as mean absolute error, root relative squared error, maximum delay, etc., as presented in Table 7. When compared to the cloud-based system, the outcomes show that the suggested system has considerably better alert production functionality, taking approximately half the time on average to generate notifications. For accuracy, the increased recall and precision values helped to minimize the error rate and reduce the false prediction rate. The proposed system’s accessibility of resources near persons, its prevention from delay of the network communication to the cloud subsystem, and its availability of higher bandwidth and low latency in the fog-subsystem have enabled the immediate alert generation from the edge of the network of persons to reduce the error, data congestion, and data volume transmission over the network for prediction. Further, the higher accuracy, recall, and specificity values suggest that the generated warnings are reliable. The proposed alert generation module proves its utility with fewer false-positive alerts, better results, lower error rates, and improved average delay or response time.
Table 7. Alert Generation Module Comparison.

4.4. Limitations and Future Directions

While the proposed system demonstrates remarkable performance, there remains room for improvement. Notably, its current scope is limited to addressing challenges specific to the dengue disease, potentially constraining its adaptability to other health-related issues. Additionally, the sensitivity of WRF model to the initial hyperparameters underscores the need for a robust optimization strategy to fine-tune these parameters effectively. To bolster the system’s overall resilience and comprehensibility, future endeavors will focus on expanding the model to incorporate features that enhance interpretability and explainability within the framework of the WRF model. This expansion aims to offer a clearer insight into the decision-making processes of the model, fostering increased trust and understanding of its outcomes across diverse user groups.

5. Conclusions

For monitoring and predicting the dengue infection, a monitoring system based on fog computing was proposed in this study. The proposed monitoring system is made up of three layers: the cloud, the fog computing gateway, and the patient information layer. Data on dengue cases were gathered and patient health was tracked using a variety of IoT devices and sensors. Additionally, a WRF classifier was created to predict dengue infection. To minimize the load on the cloud layer, the suggested WRF model was coupled with the fog computing gateway layer. Additionally, an alert message module that indicates the condition of dengue patients was also produced at the fog layer. By utilizing the data of 1254 dengue patients, the efficacy of the suggested DengueFog system was assessed and compared to traditional machine learning techniques. It has been found that the DengueFog system method attains a greater accuracy rate when compared to other classifiers. Additionally, the suggested system correctly sends end users alert messages. The proposed DengueFog system also notifies registered users of the dengue infection via proximity messages.

Author Contributions

Conceptualization, A.K. and Y.K.; methodology, J.K.S.; software, Y.K.; validation, M.K. and T.S.W.; formal analysis, M.A.; investigation, Y.K.; resources, M.K.; data curation, T.S.W.; writing—original draft preparation, J.K.S.; writing—review and editing, T.S.W. and M.A.; visualization, A.K., T.S.W. and M.A. All authors have read and agreed to the published version of the manuscript.

Funding

This work was supported by Researchers Supporting Project number (RSPD2024R968), King Saud University Riyadh, Saudi Arabia.

Data Availability Statement

Data sharing not applicable to this article as no datasets were generated or analyzed during the current study.

Conflicts of Interest

The authors declare no conflict of interest regarding the publication of this paper.

References

  1. World Health Organization. Mosquito–Borne Diseases. Available online: http://www.who.int/neglected_diseases/vector_ecology/mosquito-bornediseases/en/ (accessed on 18 March 2018).
  2. Kakarla, S.G.; Mopuri, R.; Mutheneni, S.R.; Bhimala, K.R.; Kumaraswamy, S.; Kadiri, M.R.; Gouda, K.C.; Upadhyayula, S.M. Temperature dependent transmission potential model for chikungunya in India. Sci. Total Environ. 2019, 647, 66–74. [Google Scholar] [CrossRef] [PubMed]
  3. Zhu, G.; Liu, T.; Xiao, J.; Zhang, B.; Song, T.; Zhang, Y.; Lin, L.; Peng, Z.; Deng, A.; Ma, W.; et al. Effects of human mobility, temperature and mosquito control on the spatiotemporal transmission of dengue. Sci. Total Environ. 2018, 651, 969–978. [Google Scholar] [CrossRef] [PubMed]
  4. Gupta, G.; Khan, S.; Guleria, V.; Almjally, A.; Alabduallah, B.; Siddiqui, T.; Albahlal, B.; Alajlan, S.; AL-Subaie, M. DDPM: A Dengue Disease Prediction and Diagnosis Model Using Sentiment Analysis and Machine Learning Algorithms. Diagnostics 2023, 13, 1093. [Google Scholar] [CrossRef] [PubMed]
  5. Balakrishnan, C.; Ambeth Kumar, V. IoT-Enabled Classification of Echocardiogram Images for Cardiovascular Disease Risk Prediction with Pre-Trained Recurrent Convolutional Neural Networks. Diagnostics 2023, 13, 775. [Google Scholar] [CrossRef] [PubMed]
  6. Sareen, S.; Gupta, S.K.; Sood, S.K. An intelligent and secure system for predicting and preventing Zika virus outbreak using Fog computing. Enterp. Inf. Syst. 2017, 11, 1436–1456. [Google Scholar] [CrossRef]
  7. Almufareh, M.; Tehsin, S.; Humayun, M.; Kausar, S. A Transfer Learning Approach for Clinical Detection Support of Monkeypox Skin Lesions. Diagnostics 2023, 13, 1503. [Google Scholar] [CrossRef] [PubMed]
  8. Wu, F.; Li, X.; Xu, L.; Kumari, S.; Sangaiah, A.K. A novel mutual authentication scheme with formal proof for smart health care systems under global mobility networks notion. Comput. Electr. Eng. 2018, 68, 107–118. [Google Scholar] [CrossRef]
  9. Gangula, R.; Thirupathi, L.; Parupati, R.; Sreeveda, K.; Gattoju, S. Ensemble machine learning based prediction of dengue disease with performance and accuracy elevation patterns. Mater. Today Proc. 2023, 80, 3458–3463. [Google Scholar] [CrossRef]
  10. Zargari Marandi, R.; Leung, P.; Sigera, C.; Murray, D.D.; Weeratunga, P.; Fernando, D.; Rodrigo, C.; Rajapakse, S.; MacPherson, C.R. Development of a machine learning model for early prediction of plasma leakage in suspected dengue patients. PLoS Negl. Trop. Dis. 2023, 17, e0010758. [Google Scholar] [CrossRef]
  11. Hussain, Z.; Khan, I.A.; Hassan, M. Machine learning approaches for dengue prediction: A review of algorithms and applications. Pak. Geogr. Rev. 2023, 78, 15–36. [Google Scholar]
  12. Zheng, Y.L.; Ding, X.R.; Poon, C.C.Y.; Lo, B.P.L.; Zhang, H.; Zhou, X.L.; Yang, G.Z.; Zhao, N.; Zhang, Y.T. Unobtrusive sensing and wearable devices for health informatics. IEEE Trans. Biomed. Eng. 2014, 61, 1538–1554. [Google Scholar] [CrossRef] [PubMed]
  13. Zhao, X.; Li, K.; Ang, C.K.E.; Cheong, K.H. A deep learning based hybrid architecture for weekly dengue incidences forecasting. Chaos Solitons Fractals 2023, 168, 113170. [Google Scholar] [CrossRef]
  14. Panja, M.; Chakraborty, T.; Nadim, S.S.; Ghosh, I.; Kumar, U.; Liu, N. An ensemble neural network approach to forecast Dengue outbreak based on climatic condition. Chaos Solitons Fractals 2023, 167, 113124. [Google Scholar] [CrossRef]
  15. Ghanavati, S.; Abawajy, J.H.; Izadi, D.; Alelaiwi, A.A. Cloud-assisted IoT-based health status monitoring Framework. Clust. Comput. 2017, 20, 1843–1853. [Google Scholar] [CrossRef]
  16. Majeed, M.A.; Shafri, H.Z.M.; Zulkafli, Z.; Wayayok, A. A Deep Learning Approach for Dengue Fever Prediction in Malaysia Using LSTM with Spatial Attention. Int. J. Environ. Res. Public Health 2023, 20, 4130. [Google Scholar] [CrossRef] [PubMed]
  17. Lounis, A.; Hadjidj, A.; Bouabdallah, A.; Challal, Y. Healing on the cloud: Secure cloud architecture for medical wireless sensor networks. Future Gener. Comput. Syst. 2016, 55, 266–277. [Google Scholar] [CrossRef]
  18. Santos, C.Y.; Tuboi, S.; de Abreu ADJ, L.; Abud, D.A.; Neto, A.A.L.; Pereira, R.; Siqueira, J.B. A machine learning model to assess potential misdiagnosed dengue hospitalization. Heliyon 2023, 7, e16634. [Google Scholar] [CrossRef]
  19. Sareen, S.; Sood, S.K.; Gupta, S.K. An automatic prediction of epileptic seizures using cloud computing and wireless sensor networks. J. Med. Syst. 2016, 40, 226. [Google Scholar] [CrossRef]
  20. Vairavasundaram, S.; Varadharajan, V.; Vairavasundaram, I.; Ravi, L. Data mining-based tag recommendation system: An overview. Wiley Interdiscip. Rev. Data Min. Knowl. Discov. 2015, 5, 87–112. [Google Scholar] [CrossRef]
  21. Sánchez López, B.S.; Candioti Nolberto, D.; Taquía Gutiérrez, J.A.A.; García López, Y. Traditional Machine Learning based on Atmospheric Conditions for Prediction of Dengue Presence. Comput. Y Sist. 2023, 27, 769–777. [Google Scholar] [CrossRef]
  22. Hadi, Z.A.; Dom, N.C. Development of machine learning modelling and dengue risk mapping: A concept framework. In IOP Conference Series: Earth and Environmental Science; IOP Publishing: Bristol, UK, 2023; Volume 1217, p. 012038. [Google Scholar]
  23. Shaikh, M.S.G.; SureshKumar, B.; Narang, G. Development of optimized ensemble classifier for dengue fever prediction and recommendation system. Biomed. Signal Process. Control 2023, 85, 104809. [Google Scholar] [CrossRef]
  24. Wang, X.; Gui, Q.; Liu, B.; Jin, Z.; Chen, Y. Enabling smart personalized health care: A hybrid mobilecloud approach for ECG telemonitoring. IEEE J. Biomed. Health Inform. 2014, 18, 739–745. [Google Scholar] [CrossRef] [PubMed]
  25. Lalitha, T.; Jagruthi, H.; Laxmi, V.; Bordoloi, D.; Balaji, N.A.; Rawat, R.S. Use of Machine Learning and Deep Learning Techniques to Predict Cases of Hospitalizations Caused by Dengue. In Proceedings of the 2023 International Conference on Advances in Computing, Communication and Applied Informatics (ACCAI), Chennai, India, 25–26 May 2023; IEEE: Piscataway, NJ, USA, 2023; pp. 1–7. [Google Scholar]
  26. Kapoor, R.; Ahuja, S.; Kadyan, V. Machine Learning Based Classification Algorithm for Classification of Dengue (Dengue Fever-DF, Dengue Harmonic Fever-DHF, Serve Dengue-SD). ECS Trans. 2022, 107, 4659. [Google Scholar] [CrossRef]
  27. Venkatachala Appa Swamy, M.; Periyasamy, J.; Thangavel, M.; Khan, S.; Almusharraf, A.; Santhanam, P.; Ramaraj, V.; Elsisi, M. Design and Development of IoT and Deep Ensemble Learning Based Model for Disease Monitoring and Prediction. Diagnostics 2023, 13, 1942. [Google Scholar] [CrossRef] [PubMed]
  28. Nancy, A.; Ravindran, D.; Vincent, D.; Srinivasan, K.; Chang, C. Fog-Based Smart Cardiovascular Disease Prediction System Powered by Modified Gated Recurrent Unit. Diagnostics 2023, 13, 2071. [Google Scholar] [CrossRef] [PubMed]
  29. Pati, A.; Parhi, M.; Pattanayak, B.; Singh, D.; Singh, V.; Kadry, S.; Nam, Y.; Kang, B. Breast Cancer Diagnosis Based on IoT and Deep Transfer Learning Enabled by Fog Computing. Diagnostics 2023, 13, 2191. [Google Scholar] [CrossRef] [PubMed]
  30. Pirbhulal, S.; Shang, P.; Wu, W.; Sangaiah, A.K.; Samuel, O.W.; Li, G. Fuzzy vault-based biometric security method for tele-health monitoring systems. Comput. Electr. Eng. 2018, 71, 546–557. [Google Scholar] [CrossRef]
  31. Kapoor, R.; Kadyan, V.; Ahuja, S. Weight based-artificial neural network (W-ANN) for predicting dengue using machine learning approach with Indian perspective. Int. J. Sci. Technol. Res. 2020, 9, 3290–3298. [Google Scholar]
  32. Kapoor, R.; Ahuja, S.; Kadyan, V. Contribution Title a Correlational Diagnosis Prediction Model for Detecting Concurrent Occurrence of Clinical Features of Chikungunya and Zika in Dengue Infected Patient. In Proceedings of the International Conference on Paradigms of Computing, Communication and Data Sciences: PCCDS 2020, Kurukshetra, India, 1–3 May 2020; Springer: Singapore, 2021; pp. 933–944. [Google Scholar]
  33. Dastjerdi, A.V.; Buyya, R. Fog computing: Helping the Internet of Things realize its potential. Computer 2016, 49, 112–116. [Google Scholar] [CrossRef]
  34. Albahlal, B. Emerging Technology-Driven Hybrid Models for Preventing and Monitoring Infectious Diseases: A Comprehensive Review and Conceptual Framework. Diagnostics 2023, 13, 3047. [Google Scholar] [CrossRef]
  35. Singh, S.; Bansal, A.; Sandhu, R.; Sidhu, J. Fog computing and IoT based health care support service for dengue fever. Int. J. Pervasive Comput. Commun. 2018, 14, 197–207. [Google Scholar] [CrossRef]
  36. Ali, Z.; Hossain, M.S.; Muhammad, G.; Sangaiah, A.K. An intelligent health care system for detection and classification to discriminate vocal fold disorders. Future Gener. Comput. Syst. 2018, 85, 19–28. [Google Scholar] [CrossRef]
  37. Manoharan, S.N.; Kumar, K.M.; Vadivelan, N. A Novel CNN-TLSTM Approach for Dengue Disease Identification and Prevention using IoT-Fog Cloud Architecture. Neural Process. Lett. 2023, 55, 1951–1973. [Google Scholar] [CrossRef] [PubMed]
  38. Wu, W.; Pirbhulal, S.; Sangaiah, A.K.; Mukhopadhyay, S.C.; Li, G. Optimization of signal quality over comfortability of textile electrodes for ECG monitoring in fog computing based medical applications. Future Gener. Comput. Syst. 2018, 86, 515–526. [Google Scholar] [CrossRef]
  39. Roy, C.K.; Sadiwala, R. Cloud-Fog based HealthCare Framework to Identify and Prevent Dengue Fever Outbreak. In Proceedings of the 2021 International Conference on Emerging Smart Computing and Informatics (ESCI), Pune, India, 5–7 March 2021; IEEE: Piscataway, NJ, USA, 2021; pp. 537–541. [Google Scholar]
  40. Sodhro, A.H.; Luo, Z.; Sangaiah, A.K.; Baik, S.W. Mobile edge computing based QoS optimization in medical health care applications. Int. J. Inf. Manag. 2018, 45, 308–318. [Google Scholar] [CrossRef]
  41. Shamshuzzoha, M.; Islam, M.M. Early Prediction Model of Macrosomia Using Machine Learning for Clinical Decision Support. Diagnostics 2023, 13, 2754. [Google Scholar] [CrossRef] [PubMed]
  42. Shah, T.; Yavari, A.; Mitra, K.; Saguna, S.; Jayaraman, P.P.; Rabhi, F.; Ranjan, R. Remote health care cyber-physical system: Quality of service (QoS) challenges and opportunities. IET Cyber-Phys. Syst. Theory Appl. 2016, 1, 40–48. [Google Scholar] [CrossRef]
  43. Nandyala, C.S.; Kim, H.K. From cloud to Fog and IoT-based real-time U-health care monitoring for smart homes and hospitals. Int. J. Smart Home 2016, 10, 187–196. [Google Scholar] [CrossRef]
  44. Costanzo, A.; Faro, A.; Giordano, D.; Pino, C. Mobile cyber physical systems for health care: Functions, ambient ontology and e-diagnostics. In Proceedings of the 2016 13th IEEE Annual Consumer Communications & Networking Conference (CCNC), Las Vegas, NV, USA, 9–12 January 2016; IEEE: Piscataway, NJ, USA, 2016; pp. 972–975. [Google Scholar]
  45. Oluwagbemi, O.; Oluwagbemi, F.; Abimbola, O. Ebinformatics: Ebola fuzzy informatics systems on the diagnosis, prediction and recommendation of appropriate treatments for Ebola virus disease (EVD). Inform. Med. Unlocked 2016, 2, 12–37. [Google Scholar] [CrossRef][Green Version]
  46. Sood, S.K.; Mahajan, I. Fog-cloud based cyber-physical system for distinguishing, detecting and preventing mosquito borne diseases. Future Gener. Comput. Syst. 2018, 88, 764–775. [Google Scholar] [CrossRef]
  47. Thota, C.; Sundarasekar, R.; Manogaran, G.; Varatharajan, R.; Priyan, M.K. Centralized fog computing security platform for IoT and cloud in health care system. In Fog Computing: Breakthroughs in Research and Practice; IGI Global: Hershey, PA, USA, 2018; pp. 365–378. [Google Scholar]
  48. Venckauskas, A.; Morkevicius, N.; Jukavicius, V.; Damasevicius, R.; Toldinas, J.; Grigaliunas, S. An edge-fog secure self-authenticable data transfer protocol. Sensors 2019, 19, 3612. [Google Scholar] [CrossRef] [PubMed]
  49. Parkash, O.; Abdullah, M.; Yean, C.; Sekaran, S.; Shueb, R. Development and Evaluation of an Electrochemical Biosensor for Detection of Dengue-Specific IgM Antibody in Serum Samples. Diagnostics 2021, 11, 33. [Google Scholar] [CrossRef] [PubMed]
  50. Saxena, S.K.; Elahi, A.; Gadugu, S.; Prasad, A.K. Zika virus outbreak: An overview of the experimental therapeutics and treatment. Virusdisease 2016, 27, 111–115. [Google Scholar] [CrossRef] [PubMed]
  51. Ginier, M.; Neumayr, A.; Günther, S.; Schmidt-Chanasit, J.; Blum, J. Zika without symptoms in returning travellers: What are the implications? Travel Med. Infect. Dis. 2016, 14, 16–20. [Google Scholar] [CrossRef] [PubMed]
  52. Pabbaraju, K.; Wong, S.; Gill, K.; Fonseca, K.; Tipples, G.A.; Tellier, R. Simultaneous detection of Zika, Chikungunya and Dengue viruses by a multiplex real-time RT-PCR assay. J. Clin. Virol. 2016, 83, 66–71. [Google Scholar] [CrossRef] [PubMed]
  53. Campion, M.; Bina, C.; Pozniak, M.; Hanson, T.; Vaughan, J.; Mehus, J.; Hanson, S.; Cronquist, L.; Feist, M.; Ranganathan, P.; et al. Predicting West Nile Virus (WNV) occurrences in North Dakota using data mining techniques. In Future Technologies Conference (FTC); IEEE: Piscataway, NJ, USA, 2016; pp. 310–317. [Google Scholar]
  54. Lambert, B.; Sikulu-Lord, M.T.; Mayagaya, V.S.; Devine, G.; Dowell, F.; Churcher, T.S. Monitoring the Age of Mosquito Populations Using Near-Infrared Spectroscopy. Sci. Rep. 2018, 8, 5274. [Google Scholar] [CrossRef] [PubMed]
  55. Saturi, S. Development of prediction and forecasting model for Dengue disease using machine learning algorithms. In Proceedings of the 2020 IEEE International Conference on Distributed Computing, VLSI, Electrical Circuits and Robotics (DISCOVER), Udupi, India, 30–31 October 2020; IEEE: Piscataway, NJ, USA, 2020; pp. 6–11. [Google Scholar]
  56. Devarajan, M.; Ravi, L. Intelligent cyber-physical system for an efficient detection of Parkinson disease using fog computing. Multimed. Tools Appl. 2018, 78, 32695–32719. [Google Scholar] [CrossRef]
  57. Kaur, P.; Kumar, R.; Kumar, M. A health care monitoring system using random forest and internet of things (IoT). Multimed. Tools Appl. 2019, 78, 19905–19916. [Google Scholar] [CrossRef]
  58. Parthasarathy, P.; Vivekanandan, S. A typical IoT architecture-based regular monitoring of arthritis disease using time wrapping algorithm. Int. J. Comput. Appl. 2018, 42, 222–232. [Google Scholar] [CrossRef]
  59. Tuli, S.; Basumatary, N.; Gill, S.S.; Kahani, M.; Arya, R.C.; Wander, G.S.; Buyya, R. HealthFog: An ensemble deep learning based Smart Health care System for Automatic Diagnosis of Heart Diseases in integrated IoT and fog computing environments. Future Gener. Comput. Syst. 2019, 104, 187–200. [Google Scholar] [CrossRef]
  60. Priyadarshini, R.; Barik, R.; Dubey, H. DeepFog: Fog Computing-Based Deep Neural Architecture for Prediction of Stress Types, Diabetes and Hypertension Attacks. Computation 2018, 6, 62. [Google Scholar] [CrossRef]
  61. Jabeen, F.; Maqsood, M.; Ghazanfar, M.A.; Aadil, F.; Khan, S.; Khan, M.F.; Mehmood, I. An IoT based efficient hybrid recommender system for cardiovascular disease. Peer-to-Peer Netw. Appl. 2019, 12, 1263–1276. [Google Scholar] [CrossRef]
  62. Sood, S.K.; Mahajan, I. A Fog Assisted Cyber-Physical Framework for Identifying and Preventing Coronary Heart Disease. Wirel. Pers. Commun. 2018, 101, 143–165. [Google Scholar] [CrossRef]
  63. Gu, Z.; Jiang, Y.; Zhou, M.; Gu, M.; Song, X.; Sha, L. A Cyber-Physical System Framework for Early Detection of Paroxysmal Diseases. IEEE Access 2018, 6, 34834–34845. [Google Scholar] [CrossRef]
  64. Sood, S.K.; Mahajan, I. IoT-Fog-Based Health care Framework to Identify and Control Hypertension Attack. IEEE Internet Things J. 2018, 6, 1920–1927. [Google Scholar] [CrossRef]
  65. Lakshmanaprabu, S.K.; Shankar, K.; Ilayaraja, M.; Nasir, A.W.; Vijayakumar, V.; Chilamkurti, N. Random forest for big data classification in the internet of things using optimal features. Int. J. Mach. Learn. Cybern. 2019, 10, 2609–2618. [Google Scholar] [CrossRef]
  66. Anand, L.; Ibrahim, S.S. HANN: A Hybrid Model for Liver Syndrome Classification by Feature Assortment Optimization. J. Med. Syst. 2018, 42, 211. [Google Scholar] [CrossRef]
  67. Sood, S.K.; Sood, V.; Mahajan, I. An intelligent health care system for predicting and preventing dengue virus infection. Computing 2021, 105, 1–39. [Google Scholar]
  68. Sood, S.K.; Kaur, A.; Sood, V. Energy efficient IoT-Fog based architectural paradigm for prevention of Dengue fever infection. J. Parallel Distrib. Comput. 2021, 150, 46–59. [Google Scholar] [CrossRef]
  69. Suggala, R.K.; Krishna, M.V.; Swain, S.K. Health monitoring jeopardy prophylaxis model based on machine learning in fog computing. Trans. Emerg. Telecommun. Technol. 2022, 33, e4497. [Google Scholar] [CrossRef]
  70. Gambhir, S.; Malik, S.K.; Kumar, Y. PSO-ANN based diagnostic model for the early detection of dengue disease. New Horiz. Transl. Med. 2017, 4, 1–8. [Google Scholar] [CrossRef]
  71. Gambhir, S.; Malik, S.K.; Kumar, Y. The Diagnosis of Dengue Disease. Int. J. Healthc. Inf. Syst. Inform. 2018, 13, 1–19. [Google Scholar] [CrossRef]
  72. Azman MIA, B.Z.; Sarlan, A.B. Aedes larvae classification and detection (ALCD) system by using deep learning. In Proceedings of the 2020 International Conference on Computational Intelligence (ICCI), Bandar Seri Iskandar, Malaysia, 8–9 October 2020; IEEE: Piscataway, NJ, USA, 2020; pp. 179–184. [Google Scholar]
  73. Verma, P.; Tiwari, R.; Hong, W.C.; Upadhyay, S.; Yeh, Y.H. FETCH: A deep learning-based fog computing and IoT Integrated environment for health care monitoring and diagnosis. IEEE Access 2022, 10, 12548–12563. [Google Scholar] [CrossRef]
  74. Corradi, J.P.; Thompson, S.; Mather, J.F.; Waszynski, C.M.; Dicks, R.S. Prediction of Incident Delirium Using a Random Forest classifier. J. Med. Syst. 2018, 42, 261. [Google Scholar] [CrossRef] [PubMed]
  75. Zhao, N.; Charland, K.; Carabali, M.; Nsoesie, E.O.; Maheu-Giroux, M.; Rees, E.; Yuan, M.; Garcia Balaguera, C.; Jaramillo Ramirez, G.; Zinszer, K. Machine learning and dengue forecasting: Comparing random forests and artificial neural networks for predicting dengue burden at national and sub-national scales in Colombia. PLoS Negl. Trop. Dis. 2020, 14, e0008056. [Google Scholar] [CrossRef] [PubMed]
  76. Mussumeci, E.; Coelho, F.C. Large-scale multivariate forecasting models for Dengue-LSTM versus random forest regression. Spat. Spatio-Temporal Epidemiol. 2020, 35, 100372. [Google Scholar] [CrossRef] [PubMed]
  77. Akinsal, E.C.; Haznedar, B.; Baydilli, N.; Kalinli, A.; Ozturk, A. Artificial Neural Network for the Prediction of Chromosomal Abnormalities in Azoospermic Males. Urol. J. 2018, 15, 122–125. [Google Scholar]
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