The Multifaceted Role of Confocal Laser Endomicroscopy in Head and Neck Surgery: Oncologic and Functional Insights
Abstract
:1. Introduction
2. Materials and Methods
2.1. Oncologic Surgery
2.2. Nasal Provocation Testing in Allergic Rhinitis
3. Results
3.1. Oncologic Surgery
3.1.1. Endonasal Squamous Cell Carcinoma (ESCC)
3.1.2. Oropharyngeal Squamous Cell Carcinoma (OPSCC)
3.1.3. Oral Cavity Squamous Cell Carcinoma (OCSCC)
3.2. Functional Assessment of Allergic Rhinitis
4. Discussion
4.1. CLE in Functional Assessment of Allergic Rhinitis
4.2. CLE in Head and Neck Surgery
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Healthy Mucosa | Carcinoma | |
---|---|---|
Cellular Configuration | Regular, oval to polygonal architecture | Deformation of cellular shape |
Cleary displayed boarders | Blurry to extinct boarders | |
Capillaries | Small, round to oval shaped Individually displayable | Irregular shape Formation of vascular clusters |
Absence of perivascular fluorescein leakage | Perivascular fluorescein leakage | |
Fluorescein Uptake | Homogenous distribution | Inhomogeneous distribution with Brighter aspects in areas of leakage |
Darker areas with reduced uptake |
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Wenda, N.; Fruth, K.; Fisseler-Eckhoff, A.; Gosepath, J. The Multifaceted Role of Confocal Laser Endomicroscopy in Head and Neck Surgery: Oncologic and Functional Insights. Diagnostics 2023, 13, 3081. https://doi.org/10.3390/diagnostics13193081
Wenda N, Fruth K, Fisseler-Eckhoff A, Gosepath J. The Multifaceted Role of Confocal Laser Endomicroscopy in Head and Neck Surgery: Oncologic and Functional Insights. Diagnostics. 2023; 13(19):3081. https://doi.org/10.3390/diagnostics13193081
Chicago/Turabian StyleWenda, Nina, Kai Fruth, Annette Fisseler-Eckhoff, and Jan Gosepath. 2023. "The Multifaceted Role of Confocal Laser Endomicroscopy in Head and Neck Surgery: Oncologic and Functional Insights" Diagnostics 13, no. 19: 3081. https://doi.org/10.3390/diagnostics13193081