Can Low-Iodine, Low-Radiation-Dose CT Aortogram Reliably Detect Endoleak after Endovascular Aneurysm Repair of the Aorta?
Abstract
:1. Introduction
2. Methods
2.1. Study Population
2.2. CT Technique and Acquisition Protocol
2.3. Image Reconstruction and Analysis
2.4. Radiation Dose Estimation
2.5. Statistical Analysis
3. Results
3.1. Patient Characteristics
3.2. Endoleak Analysis
Endoleak Detection by Standard-Dose CTA and DLCTA | ||||||||
SDCTA | ||||||||
Endoleak | Positive | Negative | Sensitivity | Specificity | PPV | NPV | Accuracy | |
DLCTA | Positive | 12 | 2 | 85.7% | 95.7% | 85.7% | 95.7% | 93.3% |
Negative | 2 | 44 | ||||||
Endoleak Detection by Standard-Dose CTA and DLCTA (Revised Version) | ||||||||
SDCTA | ||||||||
Endoleak | Positive | Negative | Sensitivity | Specificity | PPV | NPV | Sccuracy | |
DLCTA | Positive | 14 | 0 | 100% | 100% | 100% | 100% | 100% |
Negative | 0 | 46 |
3.3. Radiation and Contrast Medium Dose
4. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent
Data Availability Statement
Acknowledgments
Conflicts of Interest
Abbreviations
DLCTA | double-low computed tomography angiography |
SDCTA | standard-dose computed tomography angiography |
EVAR | endovascular aneurysm repair |
TEVAR | thoracic endovascular aneurysm repair |
CTA | computed tomography angiography |
CM | contrast medium |
ROI | region of interest |
CTDIvol | volume CT dose index |
DLP | dose–length product |
ED | effective dose |
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Value | SD | |
---|---|---|
Total no. of patients | 60 | |
Males | 53 | |
Females | 7 | |
Age | 64.9 | 11.3 |
BMI | 26.8 | 3.8 |
Body weight (kg) | 74.8 | 12.9 |
Body Height (cm) | 166.7 | 7.6 |
CTDIvol (mGy) | 2.85 | 1.6 |
Iodine load (mg/kg) | 199.7 | 11.2 |
Type of stent | ||
TEVAR | 36 | |
EVAR | 24 | |
Interval of CTA follow-up (days) | 306.7 | 99.5 |
Number of CTA studies | 5.2 | 1.9 |
DLCTA | SDCTA | |
---|---|---|
Arterial-phase endoleak (total) | 12 | 12 |
Certain absence | 2 | 2 |
Probable absence | 0 | 0 |
Possible presence | 3 | 3 |
Probable presence | 9 | 9 |
Delay-phase endoleak (total) | 14 | 14 |
Certain absence | 0 | 0 |
Probable absence | 0 | 0 |
Possible presence | 1 | 1 |
Probable presence | 12 | 11 |
Certain presence | 1 | 2 |
Noise level | ||
Good | 11 | 13 |
Intermediate | 3 | 1 |
Poor | 0 | 0 |
Aneurysm Size (cm) | |||||||
---|---|---|---|---|---|---|---|
Initial CTA | Midterm CTA | Last CTA | |||||
Mean | SD | Mean | SD | Mean | SD | p | |
All (n = 60) | 4.09 | 0.68 | 4.01 | 1.24 | 4.03 | 1.02 | 0.908 |
Presence of endoleak (n = 14) | 4.88 | 0.65 | 4.88 | 1.11 | 4.94 | 0.99 | 0.987 |
Absence of endoleak (n = 46) | 3.83 | 0.71 | 3.63 | 0.85 | 3.70 | 0.88 | 0.572 |
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Chen, P.-A.; Huang, E.P.; Chen, Y.-C.; Chuo, C.-C.; Huang, S.-T.; Wu, M.-T. Can Low-Iodine, Low-Radiation-Dose CT Aortogram Reliably Detect Endoleak after Endovascular Aneurysm Repair of the Aorta? Diagnostics 2023, 13, 2228. https://doi.org/10.3390/diagnostics13132228
Chen P-A, Huang EP, Chen Y-C, Chuo C-C, Huang S-T, Wu M-T. Can Low-Iodine, Low-Radiation-Dose CT Aortogram Reliably Detect Endoleak after Endovascular Aneurysm Repair of the Aorta? Diagnostics. 2023; 13(13):2228. https://doi.org/10.3390/diagnostics13132228
Chicago/Turabian StyleChen, Po-An, Eric P. Huang, Yi-Chun Chen, Chiung-Chen Chuo, Shu-Tin Huang, and Ming-Ting Wu. 2023. "Can Low-Iodine, Low-Radiation-Dose CT Aortogram Reliably Detect Endoleak after Endovascular Aneurysm Repair of the Aorta?" Diagnostics 13, no. 13: 2228. https://doi.org/10.3390/diagnostics13132228
APA StyleChen, P.-A., Huang, E. P., Chen, Y.-C., Chuo, C.-C., Huang, S.-T., & Wu, M.-T. (2023). Can Low-Iodine, Low-Radiation-Dose CT Aortogram Reliably Detect Endoleak after Endovascular Aneurysm Repair of the Aorta? Diagnostics, 13(13), 2228. https://doi.org/10.3390/diagnostics13132228