Concordance between Clinical and Pathological T and N Stages in Polish Patients with Head and Neck Cancers
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design
2.2. Data Collection
2.3. Statistical Analysis
3. Results
3.1. Characteristics of Patients
3.2. Concordance between Clinical and Pathological T Staging
3.3. Agreement between Clinical and Pathological N Staging
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Total Cohort | T-Stage Cohort | N-Stage Cohort | |
---|---|---|---|
Characteristic | n = 203 | n = 182 | n = 53 |
Age, years | 64 (56, 73) | 64 (57, 74) | 64 (59, 67) |
Women | 84 (42) | 72 (40) | 21 (40) |
Histological type | |||
Squamous cell carcinoma | 155 (76) | 148 (81) | 49 (92) |
Other | 48 (24) | 34 (19) | 4 (8) |
Grade | |||
G1 | 13 (9) | 13 (9) | 0 |
G2 | 112 (78) | 110 (78) | 38 (86) |
G3 | 19 (13) | 18 (13) | 6 (14) |
Pathological M stage | |||
Mx | 126 (62) | 109 (59) | 31 (58) |
M0 | 75 (37) | 72 (40) | 22 (42) |
M1 | 2 (1.0) | 1 (1) | 1 (2) |
Location * | |||
Tongue | 74 (36) | 70 (38) | 32 (60) |
Floor of mouth | 65 (32) | 63 (35) | 33 (62) |
Mandible | 29 (14) | 27 (15) | 14 (26) |
Lip | 29 (14) | 28 (15) | 4 (8) |
Gum | 26 (13) | 24 (13) | 8 (15) |
Maxilla | 18 (9) | 18 (10) | 0 (0) |
Palette | 16 (8) | 15 (8) | 2 (4) |
Cheek | 16 (8) | 12 (7) | 8 (15) |
Other | 29 (14) | 24 (13) | 2 (4) |
Surgery type | |||
Resection | 196 (97) | 176 (97) | 52 (100) |
Biopsy | 6 (3) | 5 (3) | 1 (2) |
Nodes dissection | |||
SND | 84 (41) | 78 (43) | 33 (62) |
RND | 55 (27) | 53 (29) | 31 (58) |
MRND | 35 (17) | 35 (19) | 20 (38) |
ERND | 4 (2) | 3 (2) | 2 (4) |
Adjuvant treatment | |||
None | 137 (68) | 121 (66) | 24 (45) |
Radiation | 57 (28) | 54 (30) | 25 (47) |
Radiation and chemotherapy | 7 (3) | 6 (3) | 3 (6) |
Chemotherapy | 2 (1) | 1 (1) | 1 (2) |
Plastic surgery | |||
Local | 121 (60) | 106 (58) | 30 (57) |
Other | 58 (28) | 56 (31) | 19 (36) |
None | 24 (12) | 20 (11) | 4 (7) |
Pathological Stage | Total, n (%) | cT1, n | cT2, n | cT3, n | cT4, n | Correct Diagnosis, n (%) | Underdiagnosis, n (%) | Overdiagnosis, n (%) |
---|---|---|---|---|---|---|---|---|
pT1 | 56 (30.8) | 28 | 24 | 3 | 1 | 28 (50) | 0 (0) | 28 (50) |
pT2 | 78 (42.9) | 13 | 44 | 21 | 0 | 44 (56.4) | 13 (16.7) | 21 (26.9) |
pT3 | 33 (18.1) | 0 | 3 | 30 | 0 | 30 (90.9) | 3 (9.1) | 0 (0) |
pT4 | 15 (8.2) | 0 | 1 | 7 | 7 | 7 (46.7) | 8 (53.3) | 0 (0) |
Pathological Stage | Total, n (%) | cN0, n | cN1, n | cN2, n | Correct Diagnosis, n (%) | Underdiagnosis, n (%) | Overdiagnosis, n (%) |
---|---|---|---|---|---|---|---|
pN0 | 3 (5.7) | 2 | 0 | 1 | 2 (66.7) | 0 (0) | 1 (33.3) |
pN1 | 26 (49.0) | 0 | 19 | 7 | 19 (73.1) | 0 (0) | 7 (26.9) |
pN2 | 24 (45.3) | 0 | 3 | 21 | 21 (87.5) | 3 (12.5) | 0 (0) |
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Chloupek, A.; Kania, J.; Jurkiewicz, D. Concordance between Clinical and Pathological T and N Stages in Polish Patients with Head and Neck Cancers. Diagnostics 2023, 13, 2202. https://doi.org/10.3390/diagnostics13132202
Chloupek A, Kania J, Jurkiewicz D. Concordance between Clinical and Pathological T and N Stages in Polish Patients with Head and Neck Cancers. Diagnostics. 2023; 13(13):2202. https://doi.org/10.3390/diagnostics13132202
Chicago/Turabian StyleChloupek, Aldona, Joanna Kania, and Dariusz Jurkiewicz. 2023. "Concordance between Clinical and Pathological T and N Stages in Polish Patients with Head and Neck Cancers" Diagnostics 13, no. 13: 2202. https://doi.org/10.3390/diagnostics13132202