Extranodal Biphenotypic Non-Hodgkin Lymphoma of the Popliteal Cavity: A Case Report and Review of Literature
Abstract
1. Introduction
2. Materials and Methods
3. Case Presentation
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Drug | Dose |
---|---|
Phase IA-IDA days 1–30 | |
Prednisone | 60 mg/m2 orally days 1–30 ° |
Vincristine | 1.5 mg/m2 IV days 1, 8, 15, 22 |
Idarubicin | 6 mg/m2 IV days 1, 8, 15, 22 |
L-Asparaginase | 10,000 UI/m2 IM days 5, 8, 11, 14, 17, 20, 23, 26 |
R2 block days 1–6 | |
Dexamethasone | 20 mg/m2 orally days 1–5 |
6-Thioguanine | 100 mg/m2 orally days 1–5 |
Vindesine | 3 mg/m2 IV day 1 |
High-dose Methotrexate | 1 g/m2 IV (36 h) day 1 |
Ifosfamide | 400 mg/m2 IV (1 h) days 1–5 |
Daunorubicin | 35 mg/m2 IV (24 h) day 5 |
L-Asparaginase | 10,000 UI/m2 IM day 6 |
R1 block days 1–6 | |
Dexamethasone | 20 mg/m2 orally days 1–5 |
6-Mercaptopurine | 100 mg/m2 orally days 1–5 |
Vincristine | 1.5 mg/m2 IV days 1 and 6 |
High-dose Methotrexate | 1 g/m2 IV (36 h) day 1 |
High-dose Cytarabine | 2 g/m2 IV (3 h), two doses 12 h apart, day 5 |
L-Asparaginase | 10,000 UI/m2 IM day 6 |
Maintenance treatment * | |
Methotrexate | 20 mg/m2/week orally |
6-Mercaptopurine | 50 mg/m2/day orally |
Reference | Age/Sex | Primary Site | Histology | Therapy | Follow-Up |
---|---|---|---|---|---|
Winter et al. (1991) [11] | 8 y/M | Buttock | ALCL (ALK ND) | CT | CR |
Evans et al. (1993) [12] | 10 y/F | Left wrist and forearm (flexor muscle) | ALCL (ALK ND) | Surg + CT | Relapse, 6 m |
Chew et al. (1999) [13] | 16 y/F | Thigh (sartorius muscle) | ALCL (ALK ND) | NS | NS |
Ishii et al. (2000) [14] | 11 y/F | Right arm | ALCL (ALK -) | CT + aHSCT | CR, 2 y |
Menon et al. (2001) [15] | 10 y/F | Left thigh (rectus femoris muscle), left arm and chest wall | ALCL (ALK ND) | CT | CR |
Driss et al. (2009) [16] | 8 y/M | Right buttock | ALCL (ALK +) | CT | CR |
Wu et al. (2009) [17] | 14 y/M | Left sacrospinalis, lumbar and femoral muscles | ALCL (ALK +) | CT | Dead, 2 m |
Rekhi et al. (2010) [18] | 9 y/F | Right pectoralis major muscle, right axilla and lateral chest wall | ALCL (ALK +) | CT | NS |
Gaiser et al. (2012) [19] | 10 y/M | Left biceps femoris muscle | ALCL (ALK +) | CT | NS |
Kounami et al. (2012) [20] | 14 y/F | Left major psoas and iliopsoas muscles | ALCL (ALK +) | CT | CR, 4 y |
Pasricha et al. (2013) [21] | 14 y/F | Right biceps brachii and right gluteal muscles, left arm, right thigh, left chest wall | ALCL (ALK +) | CT | CR, 7 m |
Gupta et al. (2022) [22] | 12 y/M | Left thigh and chest wall | ALCL (ALK +) | CT | NS |
Our case | 11 y/M | Right popliteal fossa | BLLy | CT | CR, 11 y |
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Restivo, G.A.; Mussolin, L.; D’Angelo, P.; Zin, A.; Pigazzi, M.; Carraro, E.; D’Amore, E.S.G.; Pillon, M.; Farruggia, P. Extranodal Biphenotypic Non-Hodgkin Lymphoma of the Popliteal Cavity: A Case Report and Review of Literature. Diagnostics 2022, 12, 1649. https://doi.org/10.3390/diagnostics12071649
Restivo GA, Mussolin L, D’Angelo P, Zin A, Pigazzi M, Carraro E, D’Amore ESG, Pillon M, Farruggia P. Extranodal Biphenotypic Non-Hodgkin Lymphoma of the Popliteal Cavity: A Case Report and Review of Literature. Diagnostics. 2022; 12(7):1649. https://doi.org/10.3390/diagnostics12071649
Chicago/Turabian StyleRestivo, Giulia A., Lara Mussolin, Paolo D’Angelo, Angelica Zin, Martina Pigazzi, Elisa Carraro, Emanuele S. G. D’Amore, Marta Pillon, and Piero Farruggia. 2022. "Extranodal Biphenotypic Non-Hodgkin Lymphoma of the Popliteal Cavity: A Case Report and Review of Literature" Diagnostics 12, no. 7: 1649. https://doi.org/10.3390/diagnostics12071649
APA StyleRestivo, G. A., Mussolin, L., D’Angelo, P., Zin, A., Pigazzi, M., Carraro, E., D’Amore, E. S. G., Pillon, M., & Farruggia, P. (2022). Extranodal Biphenotypic Non-Hodgkin Lymphoma of the Popliteal Cavity: A Case Report and Review of Literature. Diagnostics, 12(7), 1649. https://doi.org/10.3390/diagnostics12071649