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Formaldehyde—A Key Monad of the Biomolecular System

1
Department of Medicinal Chemistry, Faculty of Life Science University of Vienna, Althanstr. 14, Vienna 1090, Austria
2
Department of Pharmaceutical Chemistry, University of Frankfurt, Max-von-Laue-Str. 9, Frankfurt D-60438, Germany
*
Author to whom correspondence should be addressed.
Current address: Merial Ltd., 3239 Satellite Blvd., Duluth, GA 30096, USA.
This publication is dedicated to Simon Eppacher, who died tragically in the time of the preparation of this manuscript.
Life 2013, 3(3), 486-501; https://doi.org/10.3390/life3030486
Received: 2 May 2013 / Revised: 17 July 2013 / Accepted: 30 July 2013 / Published: 16 August 2013
Experiments will be presented and reviewed to support the hypothesis that the intrinsic reactivity of formaldehyde may lead to the formation of a rather comprehensive set of defined biomolecules, including D-glucose, thus fostering concepts of evolution considering the existence of a premetabolic system as a primordial step in the generation of life. View Full-Text
Keywords: formaldehyde; D-glucose; prebiotic; stereoelectronic effect; helical chirality formaldehyde; D-glucose; prebiotic; stereoelectronic effect; helical chirality
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Noe, C.R.; Freissmuth, J.; Richter, P.; Miculka, C.; Lachmann, B.; Eppacher, S. Formaldehyde—A Key Monad of the Biomolecular System. Life 2013, 3, 486-501.

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