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Review

Photoacoustic Imaging in Biomedicine and Life Sciences

by 1, 2, 1,3, 1 and 1,2,4,5,6,*
1
Opto-Electronics and Measurements, ITEE, University of Oulu, P.O. Box 4500, 90570 Oulu, Finland
2
College of Engineering and Physical Sciences, Aston University, Birmingham B4 7ET, UK
3
Research Unit of Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, P.O. Box 4500, 90014 Oulu, Finland
4
Department of Histology, Cytology and Embryology, Institute of Clinical Medicine N.V. Sklifosovsky, I.M. Sechenov First Moscow State Medical University, 119435 Moscow, Russia
5
Interdisciplinary Laboratory of Biophotonics, National Research Tomsk State University, 634050 Tomsk, Russia
6
REC Fundamental and Applied Photonics, Nanophotonics, Immanuel Kant Baltic Federal University, 236041 Kaliningrad, Russia
*
Author to whom correspondence should be addressed.
Academic Editor: Joost R. van der Vorst
Life 2022, 12(4), 588; https://doi.org/10.3390/life12040588
Received: 1 February 2022 / Accepted: 19 February 2022 / Published: 14 April 2022
(This article belongs to the Section Radiobiology and Nuclear Medicine)
Photo-acoustic imaging, also known as opto-acoustic imaging, has become a widely popular modality for biomedical applications. This hybrid technique possesses the advantages of high optical contrast and high ultrasonic resolution. Due to the distinct optical absorption properties of tissue compartments and main chromophores, photo-acoustics is able to non-invasively observe structural and functional variations within biological tissues including oxygenation and deoxygenation, blood vessels and spatial melanin distribution. The detection of acoustic waves produced by a pulsed laser source yields a high scaling range, from organ level photo-acoustic tomography to sub-cellular or even molecular imaging. This review discusses significant novel technical solutions utilising photo-acoustics and their applications in the fields of biomedicine and life sciences. View Full-Text
Keywords: photo-acoustics; opto-acoustic imaging; biomedical imaging; photo-acoustic tomography; photo-acoustic microscopy; photo-acoustic endoscopy photo-acoustics; opto-acoustic imaging; biomedical imaging; photo-acoustic tomography; photo-acoustic microscopy; photo-acoustic endoscopy
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MDPI and ACS Style

Neprokin, A.; Broadway, C.; Myllylä, T.; Bykov, A.; Meglinski, I. Photoacoustic Imaging in Biomedicine and Life Sciences. Life 2022, 12, 588. https://doi.org/10.3390/life12040588

AMA Style

Neprokin A, Broadway C, Myllylä T, Bykov A, Meglinski I. Photoacoustic Imaging in Biomedicine and Life Sciences. Life. 2022; 12(4):588. https://doi.org/10.3390/life12040588

Chicago/Turabian Style

Neprokin, Alexey, Christian Broadway, Teemu Myllylä, Alexander Bykov, and Igor Meglinski. 2022. "Photoacoustic Imaging in Biomedicine and Life Sciences" Life 12, no. 4: 588. https://doi.org/10.3390/life12040588

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