Due to its chemical properties, glyphosate [N-(phosphonomethyl)glycine] is one of the most commonly used agricultural herbicides globally. Due to risks associated with human exposure to glyphosate and its potential harmfulness, the need to develop specific, accurate, online, and sensitive methods is imperative. In accordance with this, the present review is focused on recent advances in developing nanomaterial-based sensors for glyphosate detection. Reported data from the literature concerning glyphosate detection in the different matrices using analytical methods (mostly chromatographic techniques) are presented; however, they are expensive and time-consuming. In this sense, nanosensors’ potential applications are explained to establish their advantages over traditional glyphosate detection methods. Zero-dimensional (0D), one-dimensional (1D), two-dimensional (2D), and three- dimensional (3D) materials are reviewed, from biomolecules to metallic compounds. Bionanomaterials have generated research interest due to their selectivity with respect to using enzymes, DNA, or antibodies. On the other hand, Quantum Dots also are becoming relevant for their vast surface area and good limit of detection values (in the range of pM). This review presents all the characteristics and potential applications of different nanomaterials for sensor development, bearing in mind the necessity of a glyphosate detection method with high sensitivity, selectivity, and portability.
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