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Genes 2017, 8(3), 89;

Epigenetics in Stroke Recovery

Department of Neurology, Henry Ford Health System, Detroit, MI 48202, USA
Department of Physics, Oakland University, Rochester, MI 48309, USA
Author to whom correspondence should be addressed.
Academic Editor: Dennis R. Grayson
Received: 18 November 2016 / Revised: 2 February 2017 / Accepted: 20 February 2017 / Published: 27 February 2017
(This article belongs to the Special Issue Role of Epigenetic Gene Regulation in Brain Function)
Full-Text   |   PDF [209 KB, uploaded 27 February 2017]


Abstract: While the death rate from stroke has continually decreased due to interventions in the hyperacute stage of the disease, long-term disability and institutionalization have become common sequelae in the aftermath of stroke. Therefore, identification of new molecular pathways that could be targeted to improve neurological recovery among survivors of stroke is crucial. Epigenetic mechanisms such as post-translational modifications of histone proteins and microRNAs have recently emerged as key regulators of the enhanced plasticity observed during repair processes after stroke. In this review, we highlight the recent advancements in the evolving field of epigenetics in stroke recovery. View Full-Text
Keywords: epigenetics; stroke; recovery epigenetics; stroke; recovery
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Kassis, H.; Shehadah, A.; Chopp, M.; Zhang, Z.G. Epigenetics in Stroke Recovery. Genes 2017, 8, 89.

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