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Epigenetics in Stroke Recovery

1
Department of Neurology, Henry Ford Health System, Detroit, MI 48202, USA
2
Department of Physics, Oakland University, Rochester, MI 48309, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Dennis R. Grayson
Genes 2017, 8(3), 89; https://doi.org/10.3390/genes8030089
Received: 18 November 2016 / Revised: 2 February 2017 / Accepted: 20 February 2017 / Published: 27 February 2017
(This article belongs to the Special Issue Role of Epigenetic Gene Regulation in Brain Function)
Abstract: While the death rate from stroke has continually decreased due to interventions in the hyperacute stage of the disease, long-term disability and institutionalization have become common sequelae in the aftermath of stroke. Therefore, identification of new molecular pathways that could be targeted to improve neurological recovery among survivors of stroke is crucial. Epigenetic mechanisms such as post-translational modifications of histone proteins and microRNAs have recently emerged as key regulators of the enhanced plasticity observed during repair processes after stroke. In this review, we highlight the recent advancements in the evolving field of epigenetics in stroke recovery. View Full-Text
Keywords: epigenetics; stroke; recovery epigenetics; stroke; recovery
MDPI and ACS Style

Kassis, H.; Shehadah, A.; Chopp, M.; Zhang, Z.G. Epigenetics in Stroke Recovery. Genes 2017, 8, 89.

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