Willing to Be Involved in Cancer
Abstract
:1. History
2. Willin, the Protein
3. Willin and Signalling Pathways
3.1. Hippo Pathway
3.2. Ex Is Not Fully Conserved in Mammalian Willin/FRMD6
3.3. Willin Associates with Junctional Components
3.4. Connections to the Actin Cytoskeleton
4. Willin and Cancer
Acknowledgments
Author Contributions
Conflicts of Interest
Abbreviations
3D-SIM | three-dimensional structured illumination microscopy |
aPKC | atypical Protein Kinase C |
AJ | adherens junction |
CASPR | contactin associated protein |
Ed | Echinoid |
Ex | Expanded |
EMT | epithelial-mesenchymal transition |
FAK | focal adhesion kinase |
FERM | Four point one, ezrin, radixin, moesin |
HEK | human embryonic kidney |
HM | Hippo pathway-interacting motif |
TJ | tight junction |
Y2H | yeast two hybrid |
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Gunn-Moore, F.J.; Tilston-Lünel, A.M.; Reynolds, P.A. Willing to Be Involved in Cancer. Genes 2016, 7, 37. https://doi.org/10.3390/genes7070037
Gunn-Moore FJ, Tilston-Lünel AM, Reynolds PA. Willing to Be Involved in Cancer. Genes. 2016; 7(7):37. https://doi.org/10.3390/genes7070037
Chicago/Turabian StyleGunn-Moore, Frank J., Andrew M. Tilston-Lünel, and Paul A. Reynolds. 2016. "Willing to Be Involved in Cancer" Genes 7, no. 7: 37. https://doi.org/10.3390/genes7070037