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Article

Additive and Dominance Genomic Analysis for Litter Size in Purebred and Crossbred Iberian Pigs

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Departamento de Anatomía, Embriología y Genética Animal, Facultad de Veterinaria, Instituto Agrolimentario de Aragón (IA2), 50013 Zaragoza, Spain
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Area de Producció Animal, Centre UdL-IRTA, 25198 Lleida, Spain
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Departamento de Ciència Animal, Universitat Politècnica de València, 46071 Valencia, Spain
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Departament de Ciència Animal i dels Aliments, Universitat Autònoma de Barcelona, 08193 Barcelona, Spain
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Programa de Mejora Genética “Castúa”, INGA FOOD S.A. (Nutreco), Avda. A Rúa, 2—Bajo Edificio San Marcos, 06200 Almendralejo, Spain
*
Author to whom correspondence should be addressed.
Academic Editor: Katarzyna Piórkowska
Genes 2022, 13(1), 12; https://doi.org/10.3390/genes13010012
Received: 30 November 2021 / Revised: 15 December 2021 / Accepted: 17 December 2021 / Published: 22 December 2021
(This article belongs to the Special Issue Trends and Prospects in Pig Genomics and Genetics)
INGA FOOD S. A., as a Spanish company that produces and commercializes fattened pigs, has produced a hybrid Iberian sow called CASTÚA by crossing the Retinto and Entrepelado varieties. The selection of the parental populations is based on selection criteria calculated from purebred information, under the assumption that the genetic correlation between purebred and crossbred performance is high; however, these correlations can be less than one because of a GxE interaction or the presence of non-additive genetic effects. This study estimated the additive and dominance variances of the purebred and crossbred populations for litter size, and calculated the additive genetic correlations between the purebred and crossbred performances. The dataset consisted of 2030 litters from the Entrepelado population, 1977 litters from the Retinto population, and 1958 litters from the crossbred population. The individuals were genotyped with a GeneSeek® GGP Porcine70K HDchip. The model of analysis was a ‘biological’ multivariate mixed model that included additive and dominance SNP effects. The estimates of the additive genotypic variance for the total number born (TNB) were 0.248, 0.282 and 0.546 for the Entrepelado, Retinto and Crossbred populations, respectively. The estimates of the dominance genotypic variances were 0.177, 0.172 and 0.262 for the Entrepelado, Retinto and Crossbred populations. The results for the number born alive (NBA) were similar. The genetic correlations between the purebred and crossbred performance for TNB and NBA—between the brackets—were 0.663 in the Entrepelado and 0.881 in Retinto poplulations. After backsolving to obtain estimates of the SNP effects, the additive genetic variance associated with genomic regions containing 30 SNPs was estimated, and we identified four genomic regions that each explained > 2% of the additive genetic variance in chromosomes (SSC) 6, 8 and 12: one region in SSC6, two regions in SSC8, and one region in SSC12. View Full-Text
Keywords: pig; Iberian; additive; dominance; genetic correlation; crossbreeding; genomic selection pig; Iberian; additive; dominance; genetic correlation; crossbreeding; genomic selection
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MDPI and ACS Style

Srihi, H.; Noguera, J.L.; Topayan, V.; Martín de Hijas, M.; Ibañez-Escriche, N.; Casellas, J.; Vázquez-Gómez, M.; Martínez-Castillero, M.; Rosas, J.P.; Varona, L. Additive and Dominance Genomic Analysis for Litter Size in Purebred and Crossbred Iberian Pigs. Genes 2022, 13, 12. https://doi.org/10.3390/genes13010012

AMA Style

Srihi H, Noguera JL, Topayan V, Martín de Hijas M, Ibañez-Escriche N, Casellas J, Vázquez-Gómez M, Martínez-Castillero M, Rosas JP, Varona L. Additive and Dominance Genomic Analysis for Litter Size in Purebred and Crossbred Iberian Pigs. Genes. 2022; 13(1):12. https://doi.org/10.3390/genes13010012

Chicago/Turabian Style

Srihi, Houssemeddine, José Luis Noguera, Victoria Topayan, Melani Martín de Hijas, Noelia Ibañez-Escriche, Joaquim Casellas, Marta Vázquez-Gómez, María Martínez-Castillero, Juan Pablo Rosas, and Luis Varona. 2022. "Additive and Dominance Genomic Analysis for Litter Size in Purebred and Crossbred Iberian Pigs" Genes 13, no. 1: 12. https://doi.org/10.3390/genes13010012

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