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Hybrid Block Copolymers Constituted by Peptides and Synthetic Polymers: An Overview of Synthetic Approaches, Supramolecular Behavior and Potential Applications

Departament d'Enginyeria Química, Universitat Politècnica de Catalunya, Av. Diagonal 647, E08028, Barcelona, Spain
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Polymers 2013, 5(1), 188-224; https://doi.org/10.3390/polym5010188
Received: 7 January 2013 / Revised: 1 February 2013 / Accepted: 1 February 2013 / Published: 11 February 2013
(This article belongs to the Special Issue Bioconjugates/Biohybrid Polymers)
Hybrid block copolymers based on peptides and synthetic polymers, displaying different types of topologies, offer new possibilities to integrate the properties and functions of biomacromolecules and synthetic polymers in a single hybrid material. This review provides a current status report of the field concerning peptide-synthetic polymer hybrids. The first section is focused on the different synthetic approaches that have been used within the last three years for the preparation of peptide-polymer hybrids having different topologies. In the last two sections, the attractive properties, displayed in solution or in the solid state, together with the potential applications of this type of macromolecules or supramolecular systems are highlighted. View Full-Text
Keywords: hybrid materials; peptide; synthetic polymer; supramolecular structure; synthesis; biomedical applications hybrid materials; peptide; synthetic polymer; supramolecular structure; synthesis; biomedical applications
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Morell, M.; Puiggalí, J. Hybrid Block Copolymers Constituted by Peptides and Synthetic Polymers: An Overview of Synthetic Approaches, Supramolecular Behavior and Potential Applications . Polymers 2013, 5, 188-224.

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