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Article
Peer-Review Record

A Study of Compressibility, Compactability and Mucoadhesivity of Tableting Materials for Matrix Systems Based on Chitosan

Polymers 2021, 13(21), 3636; https://doi.org/10.3390/polym13213636
by Jitka Muzikova 1, Eva Snejdrova 1,*, Juraj Martiska 2, Bara Doubkova 3 and Andrea Veris 3
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Reviewer 3: Anonymous
Polymers 2021, 13(21), 3636; https://doi.org/10.3390/polym13213636
Submission received: 24 September 2021 / Revised: 14 October 2021 / Accepted: 18 October 2021 / Published: 21 October 2021
(This article belongs to the Special Issue Functional Chitosan-Based Materials)

Round 1

Reviewer 1 Report

It is a very good study with overall adequate presentation of experimental results. Some additions are needed:

1) Authors should further emphasize on the novelty of their work.

2) Some minor typos, grammar and syntax errors should be carefully revised and corrected accordingly.

3) Reference can be even more updated (more recent relative works).

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Reviewer 2 Report

The present work highlights the chitosan and derivatives compressed tablets for drug delivery in the tract intestine. The study targets an exciting and needed topic around the world. However, several things need to be attended to before the publication. All the suggestions are highlighted in the manuscript attached. Essential suggestions are to review the grammar and English style used, add more discussion to the results and discussion section, add statistical analysis and description of the methodology used for that analysis.

Comments for author File: Comments.pdf

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Reviewer 3 Report

Dear authors!

The manuscript present new information that will open potential for chitosan application in oral drug administration. Some minor corrections required:

  1. In introduction section the more application of chitosan should be demonstrated. Please, use the recent research and review papers - 1557/s43578-021-00358-4, 10.3390/biomedicines9060588, 10.3390/ijms21020487
  2. In materials section the statistics methods description required
  3. The chapter before the subsection 3.1. is not need. It is just repeat the information from the introduction and materials section.
  4. In results description the significance of difference should be provided

 

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Round 2

Reviewer 2 Report

I appreciate that almost all the suggestions were addressed. I want to emphasize that authors should highlight the novelty of the work more in the introduction section instead of the conclusions section. However, the manuscript is ready for publication.

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