Controllable Release of Povidone-Iodine from Networked Pectin@Carboxymethyl Pullulan Hydrogel
Abstract
:1. Introduction
2. Materials and Methods
2.1. Experimental Session
2.1.1. Materials
2.1.2. Methods
Preparation of Carboxymethyl Pullulan
Preparation of Pe@CMP Hydrogel
2.2. Bioactivity of PI
2.3. Characterization and Analysis
2.3.1. Carboxylic Content and Degree of Substitution
2.3.2. Infrared Spectra (FTIR)
2.3.3. Scanning Electron Microscopy (SEM)
2.3.4. Rheological Properties
2.3.5. Solution Uptake and Swelling
2.4. Release of Povidone-Iodine
2.5. Statistical Analysis
3. Results and Discussion
3.1. Synthesis of Pe@CMP Hydrogel
3.1.1. FTIR Spectra
3.1.2. Micrographs
3.1.3. Rheological Properties
3.1.4. Solution Uptake and Swelling Properties
3.1.5. Release Properties of Povidone-Iodine (PI)
3.1.6. Kinetic and Releasing Mechanism
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Sample | Pullulan:CAA Ratio (wt:wt) | Carboxyl Content (mmol/kg) | Degree of Substitution |
---|---|---|---|
Pullulan | 1.0:0.0 | 2.2 ± 0.6 | - |
CMP1 | 1.0:1.0 | 24.2 ± 1.8 | 0.42 |
CMP2 | 1.0:1.5 | 38.5 ± 2.2 | 0.66 |
CMP3 | 1.0:2.0 | 51.2 ± 2.7 | 0.88 |
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Emam, H.E.; Mohamed, A.L. Controllable Release of Povidone-Iodine from Networked Pectin@Carboxymethyl Pullulan Hydrogel. Polymers 2021, 13, 3118. https://doi.org/10.3390/polym13183118
Emam HE, Mohamed AL. Controllable Release of Povidone-Iodine from Networked Pectin@Carboxymethyl Pullulan Hydrogel. Polymers. 2021; 13(18):3118. https://doi.org/10.3390/polym13183118
Chicago/Turabian StyleEmam, Hossam E., and Amina L. Mohamed. 2021. "Controllable Release of Povidone-Iodine from Networked Pectin@Carboxymethyl Pullulan Hydrogel" Polymers 13, no. 18: 3118. https://doi.org/10.3390/polym13183118