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Open AccessArticle

One Year Evaluation of Material Properties Changes of Polylactide Parts in Various Hydrolytic Degradation Conditions

Department of Biomedical Engineering, Faculty of Mechanical Engineering, UTP University of Science and Technology in Bydgoszcz, Prof. S. Kaliskiego 7 Avenue, 85-796 Bydgoszcz, Poland
Polymers 2019, 11(9), 1496;
Received: 20 August 2019 / Revised: 11 September 2019 / Accepted: 11 September 2019 / Published: 13 September 2019
(This article belongs to the Special Issue Biocompatible Polymers)
Biodegradable biocompatible materials are widely used in medical applications. Determining the possibility of using biodegradable materials depends on determining the changes in their parameters over time due to degradation. The current scientific research on biodegradable materials has presented results based on research methods characterized by the different geometry and cross-section size of the specimen, type of degradation medium, or different pH value of the medium or maximum degradation time. This paper presents the results of a one-year study on the influence of the type of degradation medium on the changes in mechanical behavior and the uptake of the degradation medium by biodegradable specimens with large cross-sections. In addition, a prototype of a test stand was created, which allowed for the specimens to be stored vertically to ensure regular medium exposure and eliminate the interaction of the surface of the tested specimens with the sides of the container. The obtained results allowed the statistical significance of differences in the mechanical parameters determined in the uniaxial tensile test after 2, 4, 6, 12, 26, 39, and 52 weeks of degradation to be indicated depending on the type of degradation medium. It was proven that the changes in mechanical behavior depend on the percentage change in the mass of the specimens during degradation. The percentage change in mass depends on the type of degradation medium. Based on the results of this research, it was noted that in long-term degradation above 12 weeks, buffered sodium chloride solution is the optimal choice for the degradation medium. However, distilled water or physiological saline solution can be used as an alternative during the degradation period for up to 12 weeks. View Full-Text
Keywords: polylactide; hydrolytic degradation; mechanical properties polylactide; hydrolytic degradation; mechanical properties
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MDPI and ACS Style

Andrzejewska, A. One Year Evaluation of Material Properties Changes of Polylactide Parts in Various Hydrolytic Degradation Conditions. Polymers 2019, 11, 1496.

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