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Optimizing the Extraction and Encapsulation of Mucilage from Brasenia Schreberi

College of Food Science, Sichuan Agricultural University, Yaan 625014, Sichuan, China
Author to whom correspondence should be addressed.
These authors contribute equally to this work.
Polymers 2019, 11(5), 822;
Received: 18 February 2019 / Revised: 20 April 2019 / Accepted: 28 April 2019 / Published: 7 May 2019
PDF [1941 KB, uploaded 7 May 2019]


The mucilage from Brasenia schreberi (BS) exhibits various biological activities, including antialgal, antibacterial, soluble-fiber properties, and excellent lubricating behavior. Thus, the extraction and wide use of mucilage in the food industry are crucial. In this study, the high-speed shear-assisted extraction of mucilage from BS was optimized by using response surface methodology (RSM). The optimal extraction conditions were as follows: Extraction temperature of 82 °C, extraction time of 113 min, liquid–solid ratio of 47 mL/g, and shear speed of 10,000 rpm. Under these conditions, the actual yield of BS mucilage was 71.67%, which highly matched the yield (73.44%) predicted by the regression model. Then, the BS mucilage extract was powdered to prepare the capsule, and the excipients of the capsule were screened using a single-factor test to improve the disintegration property and flowability. The final capsule formulation, which consisted of: 39% BS mucilage powder (60 meshes); 50% microcrystalline cellulose (60 meshes) as the filler; both 10% sodium starch glycolate and PVPP XL-10 (3:1, 60 meshes) as the disintegrant; both 1% colloidal silicon dioxide and sodium stearyl fumarate (1:1, 100 meshes) as the glidant by weight; were used for preparing the weights of a 320 mg/grain of capsule with 154.7 ± 0.95 mg/g polysaccharide content. Overall, the optimized extraction process had a high extraction rate for BS mucilage and the capsule formulation was designed reasonably. View Full-Text
Keywords: Brasenia schreberi; mucilage; high-speed shear-assisted extraction; optimal extraction; capsule Brasenia schreberi; mucilage; high-speed shear-assisted extraction; optimal extraction; capsule

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Luo, Q.; Wu, M.; Sun, Y.; Lv, J.; Zhang, Y.; Cao, H.; Wu, D.; Lin, D.; Zhang, Q.; Liu, Y.; Qin, W.; Chen, H. Optimizing the Extraction and Encapsulation of Mucilage from Brasenia Schreberi. Polymers 2019, 11, 822.

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