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Micromachines 2017, 8(9), 262;

Stroke Management: An Emerging Role of Nanotechnology

Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad, Gandhinagar, Gujarat 382355, India
Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad, Gandhinagar, Gujarat 382355, India
Cellular and Molecular Neurobiology Laboratory, Department of Life Science and Bioinformatics, Assam University, Assam 788011, India
Department of Neurology, University of Miami Miller School of Medicine, Miami, FL 33136, USA
Department of Neurosurgery, Boston Children’s Hospital, Harvard Medical School, Boston, MA 02115, USA
Author to whom correspondence should be addressed.
Received: 14 July 2017 / Revised: 7 August 2017 / Accepted: 9 August 2017 / Published: 28 August 2017
(This article belongs to the Special Issue Biomedical Applications of Nanotechnology and Nanomaterials)
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Stroke is among the leading causes of mortality and morbidity worldwide. Stroke incidences and associated mortality are expected to rise to 23 million and 7.8 million, respectively, by 2030. Further, the aging population, imbalanced lifestyles, and environmental factors continue to shift the rate of stroke incidence, particularly in developing countries. There is an urgent need to develop new therapeutic approaches for treating stroke. Nanotechnology is a growing field, offering an encouraging future prospect for medical research in the management of strokes. The world market for nanotechnology derived products is expected to rise manyfold in the coming decades. Different types of nanomaterials such as perfluorocarbon nanoparticles, iron oxide nanoparticles, gold nanoparticles, polymeric nanoparticles, quantum dots, nanospheres, etc. have been developed for the diagnosis as well as therapy of strokes. Today, nanotechnology has also been integrated with stem cell therapy for treating stroke. However several obstacles remain to be overcome when using such nanomaterials for treating stroke and other neurological diseases. View Full-Text
Keywords: stroke; nanotechnology; diagnosis; therapy; neuroprotection stroke; nanotechnology; diagnosis; therapy; neuroprotection

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Sarmah, D.; Saraf, J.; Kaur, H.; Pravalika, K.; Tekade, R.K.; Borah, A.; Kalia, K.; Dave, K.R.; Bhattacharya, P. Stroke Management: An Emerging Role of Nanotechnology. Micromachines 2017, 8, 262.

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