Next Article in Journal
Impact of Gastrointestinal Bacillus anthracis Infection on Hepatic B Cells
Next Article in Special Issue
Suppression of Aflatoxin Biosynthesis in Aspergillus flavus by 2-Phenylethanol Is Associated with Stimulated Growth and Decreased Degradation of Branched-Chain Amino Acids
Previous Article in Journal
Titanium Dioxide Nanoparticles (TiO2) Quenching Based Aptasensing Platform: Application to Ochratoxin A Detection
Previous Article in Special Issue
Evolution of Chemical Diversity in a Group of Non-Reduced Polyketide Gene Clusters: Using Phylogenetics to Inform the Search for Novel Fungal Natural Products

Are Some Fungal Volatile Organic Compounds (VOCs) Mycotoxins?

Department of Plant Biology and Pathology, the State University of New Jersey, Rutgers University, New Brunswick, NJ 08901, USA
The Genomics and Biomarkers Program, the John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, NJ 07601, USA
Author to whom correspondence should be addressed.
Academic Editor: Jiujiang Yu
Toxins 2015, 7(9), 3785-3804;
Received: 18 July 2015 / Revised: 28 August 2015 / Accepted: 31 August 2015 / Published: 22 September 2015
Volatile organic compounds (VOCs) are carbon-compounds that easily evaporate at room temperature. Toxins are biologically produced poisons; mycotoxins are those toxins produced by microscopic fungi. All fungi emit blends of VOCs; the qualitative and quantitative composition of these volatile blends varies with the species of fungus and the environmental situation in which the fungus is grown. These fungal VOCs, produced as mixtures of alcohols, aldehydes, acids, ethers, esters, ketones, terpenes, thiols and their derivatives, are responsible for the characteristic moldy odors associated with damp indoor spaces. There is increasing experimental evidence that some of these VOCs have toxic properties. Laboratory tests in mammalian tissue culture and Drosophila melanogaster have shown that many single VOCs, as well as mixtures of VOCs emitted by growing fungi, have toxic effects. This paper describes the pros and cons of categorizing toxigenic fungal VOCs as mycotoxins, uses genomic data to expand on the definition of mycotoxin, and summarizes some of the linguistic and other conventions that can create barriers to communication between the scientists who study VOCs and those who study toxins. We propose that “volatoxin” might be a useful term to describe biogenic volatile compounds with toxigenic properties. View Full-Text
Keywords: biogenic volatile organic compounds; fungi; mycotoxins; semiochemicals; toxins biogenic volatile organic compounds; fungi; mycotoxins; semiochemicals; toxins
MDPI and ACS Style

Bennett, J.W.; Inamdar, A.A. Are Some Fungal Volatile Organic Compounds (VOCs) Mycotoxins? Toxins 2015, 7, 3785-3804.

AMA Style

Bennett JW, Inamdar AA. Are Some Fungal Volatile Organic Compounds (VOCs) Mycotoxins? Toxins. 2015; 7(9):3785-3804.

Chicago/Turabian Style

Bennett, Joan W., and Arati A. Inamdar 2015. "Are Some Fungal Volatile Organic Compounds (VOCs) Mycotoxins?" Toxins 7, no. 9: 3785-3804.

Find Other Styles

Article Access Map by Country/Region

Only visits after 24 November 2015 are recorded.
Back to TopTop