Toxins 2015, 7(6), 2024-2050; https://doi.org/10.3390/toxins7062024
Analysis of Ergot Alkaloids
Fera Science Ltd., Sand Hutton, North Yorks YO41 1LZ, UK
Academic Editor: Christopher L. Schardl
Received: 26 February 2015 / Revised: 12 May 2015 / Accepted: 20 May 2015 / Published: 3 June 2015
(This article belongs to the Special Issue Ergot Alkaloids: Chemistry, Biology and Toxicology)
Abstract
The principles and application of established and newer methods for the quantitative and semi-quantitative determination of ergot alkaloids in food, feed, plant materials and animal tissues are reviewed. The techniques of sampling, extraction, clean-up, detection, quantification and validation are described. The major procedures for ergot alkaloid analysis comprise liquid chromatography with tandem mass spectrometry (LC-MS/MS) and liquid chromatography with fluorescence detection (LC-FLD). Other methods based on immunoassays are under development and variations of these and minor techniques are available for specific purposes. View Full-TextKeywords:
ergot; LSD; ergotamine; lysergic acid; ergovaline; mycotoxins
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Crews, C. Analysis of Ergot Alkaloids. Toxins 2015, 7, 2024-2050.