Staphylococcal Enterotoxins
Abstract
:1. Introduction
1.1. Source
Staphylococcal Enterotoxin | Feature | Binding to Class II MHC |
---|---|---|
SEA | Most common toxin associated with staphylococcal food poisoning | Alpha and beta chains [12] |
SEB | Studied as a biological weapon | Alpha chain [13] |
SEC | Commonly isolated from animals [14] | Outside the binding groove on the flanking helix from the α chain [15] |
SED | Food poisoning [16] | Alpha and Beta chains [17] |
SEE | Food poisoning [9] | Beta chain [18] |
SEF | Associated with toxic shock syndrome [8] | Binds to alpha and beta chains [19] |
SEG | Minor role in food poisoning [10] | SEB-like interaction with a chain [20] |
SEH | Food poisoning [10,11] | Alpha chain [21] |
SEI | Minor role in food poisoning [10] | Beta chain [22] |
1.2. Structure
1.3. Properties
2. SEs in Food-Borne Poisoning Associated Diarrhea
3. Staphylococcal Enterotoxins in Nosocomial and Antibiotic-Associated Diarrhea
4. Gastro-Intestinal Inflammatory Injury Associated with Enterotoxigenic Diarrheal Diseases
5. Mechanisms of Action
5.1. Emetic effect of SEs
5.2. SE superantigenic property in immunopathogenesis associated with staphylococcal diarrheal disease
5.3. Effects on professional and non-professional APCs
6. In Vivo Modeling of SE Associated Diarrheal Diseases
7. Their Potential as Agents of Biological Warfare
8. Agents that Target the Superantigen Effect of SE
9. Concluding Remarks
Acknowledgements
References
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Pinchuk, I.V.; Beswick, E.J.; Reyes, V.E. Staphylococcal Enterotoxins. Toxins 2010, 2, 2177-2197. https://doi.org/10.3390/toxins2082177
Pinchuk IV, Beswick EJ, Reyes VE. Staphylococcal Enterotoxins. Toxins. 2010; 2(8):2177-2197. https://doi.org/10.3390/toxins2082177
Chicago/Turabian StylePinchuk, Irina V., Ellen J. Beswick, and Victor E. Reyes. 2010. "Staphylococcal Enterotoxins" Toxins 2, no. 8: 2177-2197. https://doi.org/10.3390/toxins2082177
APA StylePinchuk, I. V., Beswick, E. J., & Reyes, V. E. (2010). Staphylococcal Enterotoxins. Toxins, 2(8), 2177-2197. https://doi.org/10.3390/toxins2082177