Next Article in Journal
Effects of Aflatoxin B1 and Fumonisin B1 on Blood Biochemical Parameters in Broilers
Next Article in Special Issue
The Double-Edged Sword of Autoimmunity: Lessons from Multiple Sclerosis
Previous Article in Journal
Inhibition of Hemorragic Snake Venom Components: Old and New Approaches
Previous Article in Special Issue
The Protein Kinase C Agonist PEP005 (Ingenol 3-Angelate) in the Treatment of Human Cancer: A Balance between Efficacy and Toxicity
Open AccessReview

Toxins–Useful Biochemical Tools for Leukocyte Research

Department of Dermatology, Medical School Jena, Erfurter Strasse 35, 07740, Jena, Germany
*
Author to whom correspondence should be addressed.
Toxins 2010, 2(4), 428-452; https://doi.org/10.3390/toxins2040428
Received: 8 March 2010 / Accepted: 24 March 2010 / Published: 26 March 2010
(This article belongs to the Collection Toxicity and Therapeutic Interventions in the Immune System)
Leukocytes are a heterogeneous group of cells that display differences in anatomic localization, cell surface phenotype, and function. The different subtypes include e.g., granulocytes, monocytes, dendritic cells, T cells, B cells and NK cells. These different cell types represent the cellular component of innate and adaptive immunity. Using certain toxins such as pertussis toxin, cholera toxin or clostridium difficile toxin, the regulatory functions of Gαi, Gαs and small GTPases of the Rho family in leukocytes have been reported. A summary of these reports is discussed in this review. View Full-Text
Keywords: toxins; leukocytes; signal transduction toxins; leukocytes; signal transduction
Show Figures

Graphical abstract

MDPI and ACS Style

Cubillos, S.; Norgauer, J.; Lehmann, K. Toxins–Useful Biochemical Tools for Leukocyte Research. Toxins 2010, 2, 428-452.

Show more citation formats Show less citations formats

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Search more from Scilit
 
Search
Back to TopTop