Aflatoxin Detoxification Using Microorganisms and Enzymes

Guan, Yun; Chen, Jia; Nepovimova, Eugenie; Long, Miao; Wu, Wenda; Kuca, Kamil

doi:10.3390/toxins13010046

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Aflatoxin Detoxification Using Microorganisms and Enzymes

by

Yun Guan

¹,

Jia Chen

¹,

Eugenie Nepovimova

²,

Miao Long

^1,*

,

Wenda Wu

^2,3,*

and

Kamil Kuca

^2,*

¹

Key Laboratory of Zoonosis of Liaoning Province, College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China

²

Department of Chemistry, Faculty of Science, University of Hradec Kralove, 50003 Hradec Kralove, Czech Republic

³

MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China

^*

Authors to whom correspondence should be addressed.

Toxins 2021, 13(1), 46; https://doi.org/10.3390/toxins13010046

Submission received: 13 December 2020 / Revised: 5 January 2021 / Accepted: 6 January 2021 / Published: 9 January 2021

(This article belongs to the Special Issue Occurrence, Toxicity and Mitigation of Aflatoxins)

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Abstract

Mycotoxin contamination causes significant economic loss to food and feed industries and seriously threatens human health. Aflatoxins (AFs) are one of the most harmful mycotoxins, which are produced by Aspergillus flavus, Aspergillus parasiticus, and other fungi that are commonly found in the production and preservation of grain and feed. AFs can cause harm to animal and human health due to their toxic (carcinogenic, teratogenic, and mutagenic) effects. How to remove AF has become a major problem: biological methods cause no contamination, have high specificity, and work at high temperature, affording environmental protection. In the present research, microorganisms with detoxification effects researched in recent years are reviewed, the detoxification mechanism of microbes on AFs, the safety of degrading enzymes and reaction products formed in the degradation process, and the application of microorganisms as detoxification strategies for AFs were investigated. One of the main aims of the work is to provide a reliable reference strategy for biological detoxification of AFs.

Keywords: aflatoxin; biological detoxification; detoxification mechanism; degradation products; probiotics

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MDPI and ACS Style

Guan, Y.; Chen, J.; Nepovimova, E.; Long, M.; Wu, W.; Kuca, K. Aflatoxin Detoxification Using Microorganisms and Enzymes. Toxins 2021, 13, 46. https://doi.org/10.3390/toxins13010046

AMA Style

Guan Y, Chen J, Nepovimova E, Long M, Wu W, Kuca K. Aflatoxin Detoxification Using Microorganisms and Enzymes. Toxins. 2021; 13(1):46. https://doi.org/10.3390/toxins13010046

Chicago/Turabian Style

Guan, Yun, Jia Chen, Eugenie Nepovimova, Miao Long, Wenda Wu, and Kamil Kuca. 2021. "Aflatoxin Detoxification Using Microorganisms and Enzymes" Toxins 13, no. 1: 46. https://doi.org/10.3390/toxins13010046

APA Style

Guan, Y., Chen, J., Nepovimova, E., Long, M., Wu, W., & Kuca, K. (2021). Aflatoxin Detoxification Using Microorganisms and Enzymes. Toxins, 13(1), 46. https://doi.org/10.3390/toxins13010046

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

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Aflatoxin Detoxification Using Microorganisms and Enzymes

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