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Contribution of Trans-Fatty Acid Intake to Coronary Heart Disease Burden in Australia: A Modelling Study

The George Institute for Global Health, Sydney Medical School, University of Sydney, Sydney 2042, Australia
Earth Institute and Institute of Human Nutrition, Columbia University, New York, NY 10025, USA
National Heart Foundation of Australia, Heart Health & Research, Brisbane 4006, Australia
School of Public Health, the University of Queensland, Brisbane 4006, Australia
Epigear International, Sunrise Beach 4567, Australia
Author to whom correspondence should be addressed.
Nutrients 2017, 9(1), 77;
Received: 16 November 2016 / Revised: 12 January 2017 / Accepted: 13 January 2017 / Published: 18 January 2017
Trans-fatty acids (TFAs) intake has been consistently associated with a higher risk of coronary heart disease (CHD) mortality. We provided an updated assessment of TFA intake in Australian adults in 2010 and conducted modeling to estimate CHD mortality attributable to TFA intake. Data of the 2011–2012 National Nutrition and Physical Activity Survey was used to assess TFA intake. The CHD burden attributable to TFA was calculated by comparing the current level of TFA intake to a counterfactual setting where consumption was lowered to a theoretical minimum distribution of 0.5% energy. The average TFA intake among adults was 0.59% energy, and overall 10% of adults exceeded the World Health Organization (WHO) recommended limit of 1% energy. Education and income were moderately and inversely associated with TFA intake (p-value ≤ 0.001), with one in seven adults in the lowest income and education quintile having >1% energy from TFA. Australia had 487 CHD deaths (95% uncertainty interval, 367–615) due to TFA exposure, equivalent to 1.52% (95% uncertainty limits: 1.15%–1.92%) of all CHD mortality. The relative impact of TFA exposure on CHD mortality in Australia is limited, but, in absolute terms, still substantial. Policies aimed at reducing industrial TFA exposure can reduce socioeconomic inequalities in health and may therefore be desirable. View Full-Text
Keywords: trans-fatty acid; coronary heart disease; Australia; burden; mortality trans-fatty acid; coronary heart disease; Australia; burden; mortality
MDPI and ACS Style

Wu, J.H.Y.; Zheng, M.; Catterall, E.; Downs, S.; Thomas, B.; Veerman, L.; Barendregt, J.J. Contribution of Trans-Fatty Acid Intake to Coronary Heart Disease Burden in Australia: A Modelling Study. Nutrients 2017, 9, 77.

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