Chronic Prosopis Glandulosa Treatment Blunts Neutrophil Infiltration and Enhances Muscle Repair after Contusion Injury
Abstract
:1. Introduction
2. Experimental Section
2.1. Experimental Animals
2.2. P. Glandulosa and Diclofenac Treatments
2.3. Induction of Experimental Muscle Contusion Injury and Sample Collection
2.4. Muscle Histology and Immunohistochemistry
2.5. Image Analysis
2.6. Western Blotting
2.7. Statistical Analysis
3. Results
3.1. Chronic P. Glandulosa Treatment Accelerates Repair of Muscle Ultrastructure
3.2. P. Glandulosa Treatment Blunted the Neutrophil Response to Contusion Injury
3.3. P. Glandulosa Treatment Did Not Affect Macrophage Response to Contusion Injury
3.4. ADAM12 Expression is Enhanced in Response to Chronic P. Glandulosa Treatment
3.5. Desmin Expression is Increased in Response to Chronic P. Glandulosa Treatment
4. Discussion
5. Conclusions
Supplementary Files
Supplementary File 1Supplementary File 2Acknowledgments
Author Contributions
Conflicts of Interest
References
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George, C.; Smith, C.; Isaacs, A.W.; Huisamen, B. Chronic Prosopis Glandulosa Treatment Blunts Neutrophil Infiltration and Enhances Muscle Repair after Contusion Injury. Nutrients 2015, 7, 815-830. https://doi.org/10.3390/nu7020815
George C, Smith C, Isaacs AW, Huisamen B. Chronic Prosopis Glandulosa Treatment Blunts Neutrophil Infiltration and Enhances Muscle Repair after Contusion Injury. Nutrients. 2015; 7(2):815-830. https://doi.org/10.3390/nu7020815
Chicago/Turabian StyleGeorge, Cindy, Carine Smith, Ashwin W. Isaacs, and Barbara Huisamen. 2015. "Chronic Prosopis Glandulosa Treatment Blunts Neutrophil Infiltration and Enhances Muscle Repair after Contusion Injury" Nutrients 7, no. 2: 815-830. https://doi.org/10.3390/nu7020815