The Effect of Dextrose or Protein Ingestion on Circulating Growth Differentiation Factor 15 and Appetite in Older Compared to Younger Women
Abstract
1. Introduction
2. Materials and Methods
3. Results
3.1. Appetite
3.2. GDF15
3.3. GLP-1
3.4. Glucose Metabolism
3.5. Association of Appetite, GDF15, GLP-1, Glucose and Insulin Response
4. Discussion
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Older Women n = 20 | Younger Women n = 20 | p-Value | |
---|---|---|---|
Mean ± SD | Mean ± SD | ||
Age (years) | 73.7 ± 6.30 | 25.7 ± 4.39 | |
BMI (kg/m2) | 23.9 ± 3.93 | 22.1 ± 2.33 | 0.090 |
FMI (kg/m2) | 8.65 ± 2.78 | 7.04 ± 1.73 | 0.036 |
Glucose (mmol/L) | 4.98 ± 0.44 | 4.54 ± 0.42 | 0.003 |
Insulin (µUI/mL) | 12.2 ± 11.5 | 10.3 ± 2.49 | 0.488 |
HOMA-IR | 2.70 ± 2.48 | 2.09 ± 0.58 | 0.309 |
GDF15 (pg/mL) | 802 ± 227 | 364 ± 125 | <0.001 |
GLP-1 (ng/mL) | 2.60 ± 1.37 | 3.62 ± 2.29 | 0.108 a |
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Herpich, C.; Lehmann, S.; Kochlik, B.; Kleinert, M.; Klaus, S.; Müller-Werdan, U.; Norman, K. The Effect of Dextrose or Protein Ingestion on Circulating Growth Differentiation Factor 15 and Appetite in Older Compared to Younger Women. Nutrients 2022, 14, 4066. https://doi.org/10.3390/nu14194066
Herpich C, Lehmann S, Kochlik B, Kleinert M, Klaus S, Müller-Werdan U, Norman K. The Effect of Dextrose or Protein Ingestion on Circulating Growth Differentiation Factor 15 and Appetite in Older Compared to Younger Women. Nutrients. 2022; 14(19):4066. https://doi.org/10.3390/nu14194066
Chicago/Turabian StyleHerpich, Catrin, Stephanie Lehmann, Bastian Kochlik, Maximilian Kleinert, Susanne Klaus, Ursula Müller-Werdan, and Kristina Norman. 2022. "The Effect of Dextrose or Protein Ingestion on Circulating Growth Differentiation Factor 15 and Appetite in Older Compared to Younger Women" Nutrients 14, no. 19: 4066. https://doi.org/10.3390/nu14194066
APA StyleHerpich, C., Lehmann, S., Kochlik, B., Kleinert, M., Klaus, S., Müller-Werdan, U., & Norman, K. (2022). The Effect of Dextrose or Protein Ingestion on Circulating Growth Differentiation Factor 15 and Appetite in Older Compared to Younger Women. Nutrients, 14(19), 4066. https://doi.org/10.3390/nu14194066