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Lactobacillus plantarum PS128 and Other Probiotics in Children and Adolescents with Autism Spectrum Disorder: A Real-World Experience

1
Child Neuropsychiatry Unit, IRCCS Mondino Foundation, 27100 Pavia, Italy
2
Department of Brain and Behavioral Sciences, University of Pavia, 27100 Pavia, Italy
*
Author to whom correspondence should be addressed.
Academic Editor: Vanessa Stadlbauer-Köllner
Nutrients 2021, 13(6), 2036; https://doi.org/10.3390/nu13062036
Received: 11 May 2021 / Revised: 4 June 2021 / Accepted: 12 June 2021 / Published: 14 June 2021
(This article belongs to the Section Prebiotics and Probiotics)
Autism Spectrum Disorder is a neurodevelopmental disorder. Recent data suggest that probiotics can reduce some symptoms of this disorder and Lactobacillus plantarum PS128 has been reported to be especially useful. We recruited a sample of 131 autistic children and adolescents (M:F = 122:19; age: 86.1 ± 41.1 months) and evaluated their changes after use of probiotics by mean of CGI. We found some significant improvements with very few side effects; these positive effects were more evident in younger children. Patients taking Lactobacillus plantarum PS128 had greater improvements and fewer side effects than those taking other probiotics. Our real-life data are consistent with existing literature showing a specific effect of Lactobacillus plantarum PS128 in Autism Spectrum Disorder. View Full-Text
Keywords: autism spectrum disorder; probiotics; children; adolescents; Lactobacillus plantarum PS128 autism spectrum disorder; probiotics; children; adolescents; Lactobacillus plantarum PS128
MDPI and ACS Style

Mensi, M.M.; Rogantini, C.; Marchesi, M.; Borgatti, R.; Chiappedi, M. Lactobacillus plantarum PS128 and Other Probiotics in Children and Adolescents with Autism Spectrum Disorder: A Real-World Experience. Nutrients 2021, 13, 2036. https://doi.org/10.3390/nu13062036

AMA Style

Mensi MM, Rogantini C, Marchesi M, Borgatti R, Chiappedi M. Lactobacillus plantarum PS128 and Other Probiotics in Children and Adolescents with Autism Spectrum Disorder: A Real-World Experience. Nutrients. 2021; 13(6):2036. https://doi.org/10.3390/nu13062036

Chicago/Turabian Style

Mensi, Martina M., Chiara Rogantini, Michele Marchesi, Renato Borgatti, and Matteo Chiappedi. 2021. "Lactobacillus plantarum PS128 and Other Probiotics in Children and Adolescents with Autism Spectrum Disorder: A Real-World Experience" Nutrients 13, no. 6: 2036. https://doi.org/10.3390/nu13062036

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