Next Article in Journal
Exclusive Breastfeeding Rate and Complementary Feeding Indicators in China: A National Representative Survey in 2013
Previous Article in Journal
Oleanolic Acid Exerts Osteoprotective Effects and Modulates Vitamin D Metabolism
Open AccessReview

The Evolving Role of Multivitamin/Multimineral Supplement Use among Adults in the Age of Personalized Nutrition

1
Friedman School of Nutrition Science and Policy, Tufts University, 711 Washington Street, Boston, MA 02111, USA
2
Department of Nutrition Science, Purdue University, 700 West State Street, West Lafayette, IN 47907, USA
3
Brigham and Women’s Hospital and Harvard Medical School, 900 Commonwealth Avenue East, 3rd Floor, Boston, MA 02215, USA
4
Huntsman Cancer Institute and Department of Population Health Sciences, University of Utah, 2000 Circle of Hope, Salt Lake City, UT 84112, USA
*
Author to whom correspondence should be addressed.
Nutrients 2018, 10(2), 248; https://doi.org/10.3390/nu10020248
Received: 18 December 2017 / Revised: 8 February 2018 / Accepted: 19 February 2018 / Published: 22 February 2018
Micronutrient deficiencies occur in segments of the adult population in the United States. Multivitamin/multimineral supplements (MVMS) are widely used by this population, which reduces inadequacies in micronutrient intake, but the potential for exceeding tolerable upper intake levels in others should be considered. There are concerns associated with the excessive intake of certain nutrients, particularly folic acid, and potential untoward consequences. The advent of nutrigenomics and the enhanced ability to directly study the interactions between nutrition and genetic variants and expression will allow for the conduct of more targeted studies with specific endpoints and may ultimately lead to progress in the field of personalized nutrition. The role of MVMS in health maintenance and chronic disease prevention remains controversial. Conducting studies in this area has been hampered by, among other factors, inconsistent definitions of MVMS, ranging from as few as three vitamins to broad-spectrum products containing more than two dozen vitamins and minerals. Results from some observational studies and large-scale, randomized, controlled trials suggest that MVMS may reduce the risk of some forms of cancer and, potentially, cardiovascular disease. The ongoing COcoa Supplement and Multivitamin Outcomes Study (COSMOS) is expected to build on this research and provide additional insights into these areas. View Full-Text
Keywords: dietary supplement; nutrigenomics; deficiency diseases; micronutrients; nutrition; multivitamin dietary supplement; nutrigenomics; deficiency diseases; micronutrients; nutrition; multivitamin
Show Figures

Figure 1

MDPI and ACS Style

Blumberg, J.B.; Bailey, R.L.; Sesso, H.D.; Ulrich, C.M. The Evolving Role of Multivitamin/Multimineral Supplement Use among Adults in the Age of Personalized Nutrition. Nutrients 2018, 10, 248.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop