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Clinics and Practice
Volume 8
Issue 1
10.4081/cp.2018.1007
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Clinics and Practice is published by MDPI from Volume 11 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Case Report

Primary Hypoparathyroidism Presenting as Basal Ganglia Calcification Secondary to Extreme Hypocalcemia

by
Edite Marques Mendes
1,*,
Lúcia Meireles-Brandão
1,
Carla Meira
2,
Nuno Morais
2,
Carlos Ribeiro
1 and
Diana Guerra
1
1
Department of Medicine - Medicine 1, Viana do Castelo, Portugal
2
Department of Medicine - Intermediate Care Unit, Unit of Alto Minho, Santa Luzia Hospital, Viana do Castelo, Portugal
*
Author to whom correspondence should be addressed.
Clin. Pract. 2018, 8(1), 1007; https://doi.org/10.4081/cp.2018.1007
Submission received: 17 July 2017 / Revised: 6 October 2017 / Accepted: 11 October 2017 / Published: 8 January 2018

Abstract

Hypoparathyroidism is a rare endocrine disorder characterized by low serum calcium and parathyroid hormone levels. The most common cause is parathyroid iatrogenic surgical removal. However, innumerous and rarer conditions can cause hypoparathyroidism. The authors describe a 27-year-old man that presented in emergency department with confusion, amnesia and decreased attention span. A cerebral computed tomography revealed bilateral extensive calcification in the basal ganglia. A complete work-up revealed low serum calcium, high serum phosphorus and low parathyroid hormone, leading to the diagnosis of idiopathic primary hypoparathyroidism. Initial intravenous therapy with calcium gluconate and calcitriol was administered, with clinical and analytical improvement. The authors describe a rare condition, with an exuberant cerebral presentation and extreme hypocalcemia, which did not directly correlate to the severity of symptoms. Not only this is a treatable disorder that may have catastrophic results if overlooked but also its symptoms may be completely reversed with prompt treatment.
Keywords: primary hypoparathyroidism; hypocalcemia; basal ganglia calcifications primary hypoparathyroidism; hypocalcemia; basal ganglia calcifications

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MDPI and ACS Style

Marques Mendes, E.; Meireles-Brandão, L.; Meira, C.; Morais, N.; Ribeiro, C.; Guerra, D. Primary Hypoparathyroidism Presenting as Basal Ganglia Calcification Secondary to Extreme Hypocalcemia. Clin. Pract. 2018, 8, 1007. https://doi.org/10.4081/cp.2018.1007

AMA Style

Marques Mendes E, Meireles-Brandão L, Meira C, Morais N, Ribeiro C, Guerra D. Primary Hypoparathyroidism Presenting as Basal Ganglia Calcification Secondary to Extreme Hypocalcemia. Clinics and Practice. 2018; 8(1):1007. https://doi.org/10.4081/cp.2018.1007

Chicago/Turabian Style

Marques Mendes, Edite, Lúcia Meireles-Brandão, Carla Meira, Nuno Morais, Carlos Ribeiro, and Diana Guerra. 2018. "Primary Hypoparathyroidism Presenting as Basal Ganglia Calcification Secondary to Extreme Hypocalcemia" Clinics and Practice 8, no. 1: 1007. https://doi.org/10.4081/cp.2018.1007

APA Style

Marques Mendes, E., Meireles-Brandão, L., Meira, C., Morais, N., Ribeiro, C., & Guerra, D. (2018). Primary Hypoparathyroidism Presenting as Basal Ganglia Calcification Secondary to Extreme Hypocalcemia. Clinics and Practice, 8(1), 1007. https://doi.org/10.4081/cp.2018.1007

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