Recent Advances in Ultrasound-Guided Peripheral Intravenous Catheter Insertion
Abstract
1. Introduction
2. Materials and Methods
3. Results
3.1. Clinical Efficacy and Patient Outcomes
3.1.1. Enhanced Success
3.1.2. Procedural Efficiency
3.1.3. Patient and Staff Experience
3.1.4. Complication Profile
3.1.5. Dwell Time
3.2. Application in Specific Patient Populations
3.3. Economic Implications and Cost-Effectiveness
3.4. Clinical Guidelines and Best Practices
3.4.1. Recommendations from Key Organizations
3.4.2. Training and Competency Standards
3.4.3. Aseptic Technique
3.5. Technological Advancements in Ultrasound for IV Access
4. Identification of Areas for Future Research and Development
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Public Involvement Statement
Guidelines and Standards Statement
Use of Artificial Intelligence
Conflicts of Interest
Abbreviations
C.I. | confidence interval |
DIVA | Difficult Intravenous access |
IV | Intravenous |
OR | odds ratio |
Appendix A. History and Search Details in Pubmed
#4 | Search: (#1) AND (#2) Filters: from 2010–2025: | 116 |
#3 | Search: (#1) AND (#2) | 126 |
#2 | Search: (((“ultrasound”) OR (“ultrasound guidance”)) OR (“ultrasonography”)) OR (“ultrasound-guided”) | 618,882 |
#1 | Search: (“peripheral intravenous cannulation” [All Fields] OR “peripheral intravenous access” [All Fields] OR “peripheral intravenous catheterization” [All Fields]) | 420 |
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Study (First Author, Year) | Study Design | Population/Setting | Main Findings |
---|---|---|---|
Kleidon 2024 [13] | Randomized study | Children/pediatric hospital | First-attempt success rate of 85.7% for ultrasound-guided insertion vs. 32.5% with standard technique (p < 0.001). Higher immediate cost for ultrasound-guided insertion (+US$ 5.83 per person). |
Kuo 2025 [14] | Randomized cross over study | Adults DIVA | First-attempt success rate of 63.9% for ultrasound-guided insertion vs. 13.9% with standard technique (p < 0.001). |
Godfrey 2024 [15] | Observational, retrospective | Adults DIVA | Trained nurses using ultrasound insertion with longer-length peripheral IV catheters achieved 95% first-attempt success rate. |
Elshikh 2025 [16] | Meta-analysis | Emergency and trauma patients | OR of first-attempt success with ultrasound guidance vs. standard technique: 2.1 (95% C.I. 1.65 to 2.7). |
Zaki 2025 [17] | Meta-analysis | DIVA patients | OR of first-attempt success with ultrasound guidance vs. standard technique: 5.31 (95% C.I. 2.57 to 10.96). Shorter mean time of insertion using ultrasound guidance: −9.75 min [95% C.I. −15.44 to −4.06). |
Poulsen 2023 [18] | Systematic review | Children and adults in operating rooms, emergency departments, and intensive care units | OR of first-attempt success with ultrasound guidance vs. standard technique: 3.07 (95% C.I. 1.66 to 5.65). |
D’Alessandro 2024 [19] | Randomized study | Children DIVA, emergency department | Mean procedural time of 2.7 ± 2.2 min with ultrasound guidance, vs. 10 ± 6.4 min for standard technique (p < 0.0001). |
Vinograd [20] | Randomized study | Children DIVA, emergency department | First-attempt success rate of 85.4% for ultrasound-guided insertion vs. 45.8% with standard technique, OR 1.9 (95% C.I. 1.5 to 2.4). Median procedural time of 14 min (95% C.I. 13 to 15) with ultrasound guidance vs. 28 min for standard technique (95% C.I. 21 to 31). |
Hansel 2024 [22] | Randomized study | Adult hospitalized patients | First-attempt success rate of 90.2% for ultrasound-guided insertion vs. 35.7% with standard technique (p < 0.001). Median procedural time of 5 min with ultrasound guidance, vs. 10 min for standard technique (p < 0.001). |
Salleras-Duran [23] | Randomized study | Adult emergency department DIVA patients | Higher satisfaction of patients with ultrasound-guided insertion. |
Sengul [26] | Randomized study | Outpatient chemotherapy unit | Mean (standard deviation) pain score of 1.53 ± 1.13 for ultrasound-guided insertion vs. 2.96 ± 1.77 with standard technique (p < 0.05). |
Xiong [27] | Meta-analysis | Adults | Comparison of ultrasound-guided insertion vs. standard technique, OR (95% C.I.) for failure rate 0.08 (0.04 to 0.16), for vascular injury 0.15 (0.07 to 0.32), for hematoma during the puncture process 0.24 (0.08 to 0.69). |
Au [28] | Observational study | Adult DIVA patients in 2 emergency departments | Ultrasound-guided insertion prevented the need for central venous catheter placement in 85% of patients with difficult IV access. |
Refosco [29] | Retrospective case/control study | Children DIVA, emergency department | Average duration of catheters inserted using ultrasound-guidance 5.3 ± 4.0 days with 66% of catheters removed electively vs. 2.5 ± 1.8 days and 30% for catheters inserted using standard technique (p < 0.001). |
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Bruant, A.; Normand, L. Recent Advances in Ultrasound-Guided Peripheral Intravenous Catheter Insertion. Nurs. Rep. 2025, 15, 359. https://doi.org/10.3390/nursrep15100359
Bruant A, Normand L. Recent Advances in Ultrasound-Guided Peripheral Intravenous Catheter Insertion. Nursing Reports. 2025; 15(10):359. https://doi.org/10.3390/nursrep15100359
Chicago/Turabian StyleBruant, Amélie, and Laure Normand. 2025. "Recent Advances in Ultrasound-Guided Peripheral Intravenous Catheter Insertion" Nursing Reports 15, no. 10: 359. https://doi.org/10.3390/nursrep15100359
APA StyleBruant, A., & Normand, L. (2025). Recent Advances in Ultrasound-Guided Peripheral Intravenous Catheter Insertion. Nursing Reports, 15(10), 359. https://doi.org/10.3390/nursrep15100359