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Audiology Research
Volume 9
Issue 2
10.4081/audiores.2019.231
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Audiology Research is published by MDPI from Volume 10 Issue 2 (2020). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Article

Analysis of the audiological characteristics and comorbidity in patients with chronic tinnitus

by
Silva Pavaci
1,2,*,
Federica Tortorella
1,2,
Alessandra Barbara Fioretti
3,
Anna Maria Angelone
4,
Lino Di Rienzo Businco
2,
Maria Lauriello
1 and
Alberto Eibenstein
1
1
Department of Applied Clinical and Biotechnological Sciences, University of l’Aquila, L'Aquila
2
Minimally Invasive ENT Surgery Unit, San Carlo di Nancy Hospital, Roma
3
Tinnitus Center, European Hospital, Roma
4
Department of Life, Health and Environmental Sciences, University of l’Aquila
*
Author to whom correspondence should be addressed.
Audiol. Res. 2019, 9(2), 231; https://doi.org/10.4081/audiores.2019.231
Submission received: 28 July 2019 / Revised: 7 October 2019 / Accepted: 31 October 2019 / Published: 19 December 2019

Abstract

Tinnitus is defined as perception of a sound without sound stimulation. This study aims to investigate the correlation between chronic tinnitus and the most significant clinical comorbidities and pharmacological treatments. We recruited 130 consecutive outpatients with a tinnitus for least from three months and 100 subjects without tinnitus. All patients had a full medical and audiological evaluation and all filled in Tinnitus Handicap Inventory questionnaire and Khalfa’s Hyperacusis questionnaire. We also analyzed the qualitative variables: audiometry exam, tinnitus characteristics and psychometric questionnaires. Univariate logistic regression was performed to evaluate the associations between the presence of tinnitus and the presence of comorbidities and drug intake. The statistical analysis provided the following results in the group of patients with tinnitus. We obtained an Odds Ratio statistically significant for the following categories taken into consideration: the presence of anxiety and depression, neurological diseases, headache, temporomandibular joint (TMJ) disorders, intake of levothyroxine and proton-pump inhibitor. In this study, we tried to evaluate the audiological characteristics in the subjects affected by chronic tinnitus in order to find a possible correlation with the comorbidities and any drugs intake. We found a statistically significant correlation between tinnitus and comorbidities like anxiety, depression, TMJ disorders, dysthyroidism, headache and levothyroxine and PPI intake.
Keywords: Tinnitus; comorbidity; drugs medication; levothyroxine; proton-pump inhibitor. Tinnitus; comorbidity; drugs medication; levothyroxine; proton-pump inhibitor.

Share and Cite

MDPI and ACS Style

Pavaci, S.; Tortorella, F.; Fioretti, A.B.; Angelone, A.M.; Di Rienzo Businco, L.; Lauriello, M.; Eibenstein, A. Analysis of the audiological characteristics and comorbidity in patients with chronic tinnitus. Audiol. Res. 2019, 9, 231. https://doi.org/10.4081/audiores.2019.231

AMA Style

Pavaci S, Tortorella F, Fioretti AB, Angelone AM, Di Rienzo Businco L, Lauriello M, Eibenstein A. Analysis of the audiological characteristics and comorbidity in patients with chronic tinnitus. Audiology Research. 2019; 9(2):231. https://doi.org/10.4081/audiores.2019.231

Chicago/Turabian Style

Pavaci, Silva, Federica Tortorella, Alessandra Barbara Fioretti, Anna Maria Angelone, Lino Di Rienzo Businco, Maria Lauriello, and Alberto Eibenstein. 2019. "Analysis of the audiological characteristics and comorbidity in patients with chronic tinnitus" Audiology Research 9, no. 2: 231. https://doi.org/10.4081/audiores.2019.231

APA Style

Pavaci, S., Tortorella, F., Fioretti, A. B., Angelone, A. M., Di Rienzo Businco, L., Lauriello, M., & Eibenstein, A. (2019). Analysis of the audiological characteristics and comorbidity in patients with chronic tinnitus. Audiology Research, 9(2), 231. https://doi.org/10.4081/audiores.2019.231

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